Evidence map›Paper›PMID 42211547›Full record

ReviewFrontiers in human neuroscience2026

Motor intervention therapy for children with developmental coordination disorder: from behavioral improvement to neuroplasticity mechanisms.

Zhiguang Ji, Liyan Wang, Le Lu, Chenping Zhang, Hongbiao Wang

Abstract readReview
In one paragraph

Review in Frontiers in human neuroscience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Zhiguang JiDepartment of Physical Education, Shanghai University of Medicine and Health Sciences, Shanghai, China.
Liyan WangCollege of Rehabilitation Sciences, Shanghai University of Medicine and Health Sciences, Shanghai, China.
Le LuDepartment of Physical Education, Shanghai University of Medicine and Health Sciences, Shanghai, China.
Chenping ZhangDepartment of Physical Education, Shanghai University of Medicine and Health Sciences, Shanghai, China.
Hongbiao WangDepartment of Physical Education, Shanghai University of Medicine and Health Sciences, Shanghai, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Developmental Coordination Disorder (DCD) is a common neurodevelopmental disorder characterized by significantly delayed motor coordination, often accompanied by cognitive deficits and psychosocial adaptation issues, severely impacting children's lifelong development. Motor intervention serves as the primary treatment strategy for DCD, encompassing task-oriented, process-oriented, and technology-assisted paradigms. Existing evidence indicates that structured motor interventions effectively enhance motor skills, executive function, and social engagement in children with DCD. The core mechanism lies in inducing neuroplasticity-encompassing both functional reorganization (e.g., normalization of motor network activation, improved inter-regional connectivity) and structural changes (e.g., increased grey matter volume in key brain regions, optimized white matter microstructure). These changes ultimately facilitate behavioral improvement through optimized internal models and enhanced cognitive-motor coupling. This paper constructs an integrated "motor intervention-neuroplasticity-functional improvement" model, reviews intervention efficacy and mechanisms, identifies current research limitations in sample size, causal inference, and long-term follow-up, and outlines future directions such as precision rehabilitation and technology integration. It provides theoretical support for evidence-based interventions in DCD.

Indexed as

behavioral improvementbrain remodelingcognitive functiondevelopmental coordination disordermotor interventionneuroplasticity

Identifiers

PMID42211547
PMCPMC13212326

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.