Evidence map›Paper›PMID 42211538›Full record

ArticleFrontiers in digital health2026

Recruitment strategies and participant motivations in a digital randomized controlled trial for the prevention of anxiety disorders: the prevANS study.

Cristina García-Huércano, Sonia Conejo-Cerón, Alberto Rodríguez-Morejón, Carmela Martínez-Vispo, Natalia Sánchez-Aguadero, Olaya Tamayo-Morales, Patricia Moreno-Peral

Abstract read
In one paragraph

Article in Frontiers in digital health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Cristina García-HuércanoInstituto de Investigación Biomédica de Málaga y Plataforma en Nanomedicina (IBIMA Plataforma BIONAND), Málaga, Spain.
Sonia Conejo-CerónInstituto de Investigación Biomédica de Málaga y Plataforma en Nanomedicina (IBIMA Plataforma BIONAND), Málaga, Spain.
Alberto Rodríguez-MorejónInstituto de Investigación Biomédica de Málaga y Plataforma en Nanomedicina (IBIMA Plataforma BIONAND), Málaga, Spain.
Carmela Martínez-VispoInstitute of Psychology (IPsiUS), University of Santiago de Compostela (USC), Santiago de Compostela, Spain.
Natalia Sánchez-AguaderoResearch Network on Chronicity, Primary Care, Prevention and Health Promotion (RICAPPS), Barcelona, Spain.
Olaya Tamayo-MoralesResearch Network on Chronicity, Primary Care, Prevention and Health Promotion (RICAPPS), Barcelona, Spain.
Patricia Moreno-PeralInstituto de Investigación Biomédica de Málaga y Plataforma en Nanomedicina (IBIMA Plataforma BIONAND), Málaga, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Anxiety disorders are among the most prevalent mental health problems worldwide, and access to effective treatment is not always available. Preventive interventions need to be scalable and cost-effective, which can be achieved through communication and information technologies. However, recruiting participants for digital prevention trials remains a major methodological challenge. Aim: To evaluate the performance of different approaches to recruiting participants for a digital preventive intervention for anxiety (the prevANS trial), and to assess participants' motivations for enrolling in the trial. Methods: Descriptive analyses were conducted to evaluate the performance of each recruitment strategy (number of potential participants attracted per week). Quantitative data were obtained from website records of individuals initiating the online screening process while each strategy was active, and self-reported information on how participants learned about the study. Baseline group differences between the intervention and control groups were examined using chi-square and Mann-Whitney Results: Over a 26-month recruitment period, 6,017 individuals initiated screening and 1,054 participants were enrolled (17.5% conversion rate). The most effective strategies for attracting potential participants were social media and university dissemination. Self-reported data also indicated that word of mouth had a notable impact on recruitment. The final sample was mainly composed of women and highly educated participants, and the intervention and control groups were balanced across all variables except for age. Thematic analysis revealed three main motivations for enrollment: helping others, health related issues, and own benefits. Conclusion: Recruitment strategies should be tailored to the target population, as their performance may vary across groups. Involving users through co-design and co-creation can enhance both the intervention and the identification of effective recruitment channels in digital trials.

Indexed as

anxiety disordersappdigital interventionspreventionrandomized controlled trialrecruitment strategies

Identifiers

PMID42211538
PMCPMC13212293

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.