Evidence map›Paper›PMID 42211536›Full record

ArticleFrontiers in molecular neuroscience2026

Caffeine attenuates cisplatin induced microglial reactivity and cognitive dysfunction.

Alfredo Oliveros, Ivan Loncar, Marwan Mostafa, Michael Poleschuk, Ana M Corujo, Bo Qin, Juhyun Song, Max A Tischfield, Mi-Hyeon Jang

Abstract read
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In one paragraph

Article in Frontiers in molecular neuroscience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Alfredo OliverosDepartment of Neurosurgery, Robert Wood Johnson Medical School, Rutgers University, Piscataway, NJ, United States.
Ivan LoncarDepartment of Neurosurgery, Robert Wood Johnson Medical School, Rutgers University, Piscataway, NJ, United States.
Marwan MostafaDepartment of Neurosurgery, Robert Wood Johnson Medical School, Rutgers University, Piscataway, NJ, United States.
Michael PoleschukDepartment of Neurosurgery, Robert Wood Johnson Medical School, Rutgers University, Piscataway, NJ, United States.
Ana M CorujoDepartment of Neurological Surgery, Mayo Clinic College of Medicine, Rochester, MN, United States.
Bo QinSection of Cancer Epidemiology and Health Outcomes, Rutgers Cancer Institute, New Brunswick, NJ, United States.
Juhyun SongDepartment of Anatomy, Chonnam National University Medical School, Hwasun, Republic of Korea.
Max A TischfieldDepartment of Cell Biology and Neuroscience, School of Arts and Sciences, Rutgers University, Piscataway, NJ, United States.
Mi-Hyeon JangDepartment of Neurosurgery, Robert Wood Johnson Medical School, Rutgers University, Piscataway, NJ, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Advances in cancer treatment by chemotherapy, radiation, and personalized targeted therapy have significantly improved cancer survivorship. Life extension from chemotherapy is arguably the most accessible non-surgical treatment strategy, but it is accompanied by neurotoxic sequelae that are detrimental to cognitive function in survivors. Using the platinum-based drug cisplatin to model chemotherapy induced cognitive impairments (CICI; also called chemobrain) in mice, we recently identified that elevated hippocampal adenosine A

Indexed as

adenosine receptor 2Acaffeinechemobrainchemofogcisplatinmicroglianeurogenesis

Identifiers

PMID42211536
PMCPMC13212328

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.