ArticleFrontiers in oncology2026
Abdominal complete hydatidiform mole following uterine evacuation: a case report.
Article in Frontiers in oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Hydatidiform mole (HM) is a form of gestational trophoblastic disease that most commonly develops within the uterine cavity. Ectopic hydatidiform mole is exceedingly rare, and abdominal implantation represents one of its rarest presentations. Due to nonspecific clinical manifestations and the lack of characteristic imaging features, abdominal HM poses significant diagnostic challenges and is frequently diagnosed only after surgical exploration. Case presentation: We report the case of a 24-year-old woman with a history of polycystic ovary syndrome who conceived following ovulation induction therapy. She was diagnosed with complete hydatidiform mole and underwent uterine evacuation. Postoperatively, serum human chorionic gonadotropin (hCG) levels failed to decline appropriately and subsequently rebounded. Imaging studies revealed no definitive intrauterine lesions, but a persistent mass was detected posterior to the uterus. Diagnostic laparoscopy identified an isolated lesion located in the rectouterine pouch and rectal peritoneum, without any communication with the uterine cavity or adnexa. The lesion was completely excised laparoscopically. Histopathological examination demonstrated hydropic swelling of chorionic villi with diffuse trophoblastic proliferation, and immunohistochemical analysis revealed absence of p57^KIP2 expression, confirming the diagnosis of abdominal complete hydatidiform mole. Following surgery, serum hCG levels rapidly declined and returned to normal. The patient recovered uneventfully and remained under close postoperative hCG surveillance, with no evidence of persistent or recurrent disease. Conclusions: Abdominal complete hydatidiform mole is a rare but important diagnostic consideration in patients with persistent or rising serum hCG levels after molar evacuation. This case highlights the limitations of imaging modalities and underscores the critical role of postoperative hCG monitoring in the early detection of ectopic molar disease.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.