Evidence map›Paper›PMID 42211499›Full record

ArticleFrontiers in oncology2026

Pan-tumor validation of FoundationOne

Allison van den Hout, Richard S P Huang, Caleb Ho, David L Smith, Douglas A Mata, Baljinder Kaur, Sameera R Wijayawardana, Jennifer Wright, Anna M Szpurka, Douglas I Lin

Abstract read
In one paragraph

Article in Frontiers in oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Allison van den HoutFoundation Medicine, Inc., Boston, MA, United States.
Richard S P HuangFoundation Medicine, Inc., Boston, MA, United States.
Caleb HoFoundation Medicine, Inc., Boston, MA, United States.
David L SmithFoundation Medicine, Inc., Boston, MA, United States.
Douglas A MataFoundation Medicine, Inc., Boston, MA, United States.
Baljinder KaurFoundation Medicine, Inc., Boston, MA, United States.
Sameera R WijayawardanaEli Lilly and Company, Indianapolis, IN, United States.
Jennifer WrightEli Lilly and Company, Indianapolis, IN, United States.
Anna M SzpurkaEli Lilly and Company, Indianapolis, IN, United States.
Douglas I LinFoundation Medicine, Inc., Boston, MA, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Methods: The F1CDx assay produces chimeric read pairs to determine fusion status. Additionally, a study of F1CDx was conducted as a retrospective clinical bridging study based on LIBRETTO-001 clinical trial samples and data. Results: Across solid tumor types, F1CDx demonstrated a high concordance for Conclusions: F1CDx is an accurate, reliable, FDA- and MHLW-approved method for the pan-tumor identification of

Indexed as

companion diagnostic (CDx)comprehensive genomic profiling (CGP)FoundationOne®CDxRET fusionvalidation

Identifiers

PMID42211499
PMCPMC13212050

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.