Evidence map›Paper›PMID 42211433›Full record

ArticleCase reports in critical care2026

Treatment of Heparin-Induced Thrombocytopenia in the Setting of Venoarterial Extracorporeal Membrane Oxygenation as a Bridge to Orthotopic Heart Transplant.

Ethan J Han, Nicholas Kalekas, Matthew S Vandiver

Abstract read
In one paragraph

Article in Case reports in critical care, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Ethan J HanDepartment of Anesthesiology and Perioperative Medicine, University of California, Los Angeles, Los Angeles, CA, USA, berkeley.edu.ORCID https://orcid.org/0000-0002-0981-4858
Nicholas KalekasDepartment of Anesthesiology and Perioperative Medicine, University of California, Los Angeles, Los Angeles, CA, USA, berkeley.edu.ORCID https://orcid.org/0009-0000-4209-6889
Matthew S VandiverDepartment of Anesthesiology and Perioperative Medicine, University of California, Los Angeles, Los Angeles, CA, USA, berkeley.edu.ORCID https://orcid.org/0000-0002-7272-6332

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Heparin-induced thrombocytopenia (HIT) is a highly impactful prothrombotic condition produced by antibody formation after heparin administration, which leads to platelet activation and both thrombocytopenia and paradoxical thrombosis. HIT has a relatively high mortality rate and greatly complicates anticoagulation strategy in patients requiring surgeries necessitating cardiopulmonary bypass, such as orthotopic heart transplant (OHT). Here, we present a small case report involving two patients who developed HIT in the setting of ongoing venoarterial extracorporeal membrane oxygenation (VA-ECMO) support for cardiogenic shock while being listed for OHT and the novel plasma exchange strategy that was utilized to manage their HIT through the transplant process.

Identifiers

PMID42211433
PMCPMC13214974

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.