Evidence map›Paper›PMID 42211376›Full record

ArticleRSC advances2026

Electrospun Zn-cobimetinib-levofloxacin-PVA/PVP nanofibers for skin-targeted anticancer and antimicrobial applications.

Zainb A Talib, Ahmed Kareem Obaid Aldulaimi, Farag M A Altalbawy, Jameel M A Sulaiman, Rafid Jihad Albadr, Waam Mohammed Taher, Nasr Saadoun Abd, Hiba Mushtaq, Hadil Faris Alotaibi, Adama Faye

Abstract read
In one paragraph

Article in RSC advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Zainb A TalibDepartment of Medical Analysis, Medical Laboratory Technique College, The Islamic University Najaf Iraq.
Ahmed Kareem Obaid AldulaimiDepartment of Pharmacy, Al-Zahrawi University College Karbala Iraq.
Farag M A AltalbawyDepartment of Chemistry, University College of Duba, University of Tabuk Tabuk Saudi Arabia.ORCID https://orcid.org/0009-0008-2875-9939
Jameel M A SulaimanHealth and Medical Techniques College, Alnoor University Nineveh Iraq.
Rafid Jihad AlbadrCollege of Pharmacy, Ahl Al Bayt University Kerbala Iraq.
Waam Mohammed TaherCollege of Nursing, National University of Science and Technology Dhi Qar Iraq.
Nasr Saadoun AbdMedical Technical College, Al-Farahidi University Iraq.
Hiba MushtaqGilgamesh Ahliya University Baghdad Iraq.
Hadil Faris AlotaibiDepartment of Pharmaceutical Sciences, College of Pharmacy, Princess Nourah Bint AbdulRahman University Riyadh 11671 Saudi Arabia.
Adama FayeDepartment of Pharmacy, Faculty of Medicine, Pharmacy and Odonto-Stomatology, University of Ziguinchor Ziguinchor Senegal khrshdmuzammil@gmail.com.ORCID https://orcid.org/0009-0002-6342-4452

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The development of wound dressings that simultaneously combat skin cancer and prevent bacterial infection remains an unmet clinical need. Herein, we report electrospun nanofibrous composites composed of polyvinyl alcohol (PVA) and polyvinyl pyrrolidone (PVP) co-loaded with cobimetinib, levofloxacin, and zinc nitrate. Cobimetinib's tetradentate coordination enabled the formation of a stable Zn-based coordination complex within the polymeric matrix (Zn-cobimetinib-levofloxacin-PVA/PVP nanofibers), ensuring stable incorporation of the drugs while preserving their biological activity. Physicochemical characterization, including scanning electron microscopy (SEM), energy eispersive X-ray (EDX), Fourier-transform infrared spectroscopy (FT-IR), X-ray diffraction (XRD), thermogravimetric analysis (TGA), differential thermogravimetric (DTG), differential scanning calorimetry (DSC), ultraviolet and visible-spectroscopy (UV-vis), tensile strength, contact angle, N

Identifiers

PMID42211376
PMCPMC13213560

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.