Evidence map›Paper›PMID 42211326›Full record

ArticleBrain & spine2026

Life-size 3D modeling for C1-C2 fixation planning: A preoperative tool for atlantoaxial stabilization techniques.

Bekir Can Kendirlioglu, Umid Sulaimanov, Mehmet Hakan Sahin, Taha Sukru Korkmaz, Abdullah Keles, Ufuk Erginoglu, Evren Aydogmus, Garret P Greeneway, Mohamed A Zaazoue, Mustafa K Baskaya

Abstract read
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Article in Brain & spine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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0 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

10 authors.

Bekir Can KendirliogluDepartment of Neurological Surgery, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI, 53792, USA.
Umid SulaimanovDepartment of Neurological Surgery, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI, 53792, USA.
Mehmet Hakan SahinDepartment of Neurosurgery, Atlas University, Istanbul, Türkiye.
Taha Sukru KorkmazDepartment of Neurological Surgery, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI, 53792, USA.
Abdullah KelesDepartment of Neurological Surgery, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI, 53792, USA.
Ufuk ErginogluDepartment of Neurological Surgery, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI, 53792, USA.
Evren AydogmusUniversity of Health Sciences, Kartal Dr. Lutfi Kirdar City Hospital, Department of Neurosurgery, Istanbul, 34865, Turkey.
Garret P GreenewayDepartment of Neurological Surgery, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI, 53792, USA.
Mohamed A ZaazoueDepartment of Neurological Surgery, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI, 53792, USA.
Mustafa K BaskayaDepartment of Neurological Surgery, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI, 53792, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Spine instrumentation can be performed with intraoperative computed tomography (CT) guidance, fluoroscopy guidance, or freehand techniques. Surgical fixation of the atlantoaxial (C1-C2) junction without CT guidance remains technically challenging due to complex anatomy and proximity to critical neurovascular structures. Research question: To evaluate the feasibility of low-cost, patient-specific three-dimensional (3D)-printed anatomical models for preoperative planning of C1-C2 instrumentation. Material and methods: High-resolution CT and CT angiography data from 20 individuals were used to generate patient-specific 3D models of the C1-C2 vertebrae and vertebral arteries using open-source segmentation software (3D Slicer®). Models were produced as life-size replicas, with multiple fixation techniques simulated and screw angulations measured in axial and sagittal planes. Results: Twenty patient-specific C1-C2 anatomical models were successfully produced and instrumented. Screw angulations and lengths across all fixation techniques-including C1 lateral mass, C2 pedicle, pars, translaminar, and transarticular screws-remained within established safe anatomical ranges. Each model required approximately 215 min of active printing time and a total hands-on preparation time of approximately 275-320 min, with an additional 24-h curing period for silicone processing. The material cost per model was approximately USD 0.56 using a desktop fused deposition modeling printer. Discussion and conclusion: Low-cost, patient-specific 3D-printed models provide anatomically consistent, life-size representations of the complex atlantoaxial region. These models may represent a practical adjunct for surgical planning, feasibility assessment, and preoperative rehearsal for various C1-C2 fixation strategies without advanced intraoperative technology. Further studies are needed to evaluate their clinical impact.

Indexed as

3D printingAtlantoaxial instabilityC1–C2 fixationOpen-source softwarePatient-specific modelsSurgical simulation

Identifiers

PMID42211326
PMCPMC13213741

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.