Evidence map›Paper›PMID 42211287›Full record

ArticleCureus2026

Artificial Intelligence-Driven Skin Parameter Assessment in Indian Adults: Establishing Population-Specific Reference Data for Clinical Dermatology.

Saurabh Arora, Neha Arora, Manoj Karwa, Surya T Reddy

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Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Saurabh AroraResearch, Auriga Research Pvt. Ltd., Delhi, IND.
Neha AroraNingen Skin Sciences, Arbro Pharmaceuticals Pvt. Ltd., Delhi, IND.
Manoj KarwaClinical Trial and Pharmacovigilance, Auriga Research Pvt. Ltd., Delhi, IND.
Surya T ReddyClinical Research, Auriga Research Pvt. Ltd., Gurugram, IND.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background Artificial intelligence (AI)-based skin analysis enables objective, large-scale assessment of dermatologic features; however, population-specific normative reference ranges for Indian skin remain limited. This exploratory study aimed to establish percentile-based reference distributions for facial skin parameters in Indian adults, predominantly comprising Fitzpatrick skin types III-V, who demonstrate distinct pigmentary and aging patterns that are underrepresented in the existing literature. Methods This retrospective, cross-sectional study analyzed de-identified facial scan data from 20,914 healthy Indian adults (≥18 years) obtained through the SkinSensAI™ platform (Ningen Skin Sciences Pvt. Ltd., New Delhi, India), of whom 20,913 with complete age data were included in age-stratified analyses. Facial images were processed using an AI engine to generate standardized severity scores (1-5 scale) for 12 facial skin parameters. Descriptive statistics, age-, gender-, and Fitzpatrick-stratified analyses, and inter-parameter correlations were performed in accordance with the Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) guidelines. Results Dark circles and enlarged pores emerged as the most prevalent concerns, while wrinkle severity remained low in participants younger than 45 years. Wrinkles showed the strongest correlation with age (r = 0.57, p < 0.001). Male participants exhibited significantly higher scores for pores, spots, wrinkles, and skin laxity than female participants (p < 0.001). Darker Fitzpatrick skin types demonstrated a higher pigmentary burden, whereas wrinkle severity was relatively lower, consistent with melanin-associated photoprotection. Distinct correlation clusters reflected aging-related, pigmentation-sebaceous, and independent skin domains. Conclusion This study establishes the first large-scale, AI-derived reference database of facial skin parameters specific to the Indian population. These population-specific benchmarks support objective dermatologic assessment, personalized patient counseling, and equitable AI application in clinical dermatology.

Indexed as

artificial intelligenceclinical dermatologydermatologyepidemiologyethnic skinpopulation healthreference dataskin assessment

Identifiers

PMID42211287
PMCPMC13215660

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.