Evidence map›Paper›PMID 42211217›Full record

ArticleInternational journal of ophthalmology2026

Correlation between pathogenic

Yan Gao, Dan-Ting Lin, Tao Zhou, Lin-Hui He, Ke-Xin Zhao, Xiao-Wei Yu, Lin Deng, Zhi-Gang Fan, Yan Shi

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of ophthalmology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yan GaoBeijing Institute of Ophthalmology, Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing 100730, China.
Dan-Ting LinBeijing Institute of Ophthalmology, Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing 100730, China.
Tao ZhouBeijing Institute of Ophthalmology, Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing 100730, China.
Lin-Hui HeBeijing Institute of Ophthalmology, Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing 100730, China.
Ke-Xin ZhaoBeijing Institute of Ophthalmology, Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing 100730, China.
Xiao-Wei YuBeijing Institute of Ophthalmology, Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing 100730, China.
Lin DengBeijing Institute of Ophthalmology, Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing 100730, China.
Zhi-Gang FanBeijing Institute of Ophthalmology, Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing 100730, China.
Yan ShiBeijing Institute of Ophthalmology, Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing 100730, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo explore the genetic variants of trabeculodysgenesis under ultrasound biomicroscopy (UBM) and its association with surgical outcomes in patients with primary congenital glaucoma (PCG).

methodsIn this prospective case series, consecutive patients with PCG underwent microcatheter-assisted trabeculotomy (MAT) and followed for at least 24-month after surgery. All participants underwent UBM and whole-exome sequencing prior to MAT and were classified into two groups with severe trabeculodysgenesis or mild trabeculodysgenesis under UBM. Surgical success was defined as a postoperative IOP of ≤21 mm Hg with at least a 20% reduction from preoperative IOP without additional medical or surgical therapy.

resultsSevere trabeculodysgenesis was observed in 23 (40%) eyes of 14 patients (median age: 57mo, range: 3-169mo; 11 males) with 8 carrying causative

conclusionPCG patients with severe trabeculodysgenesis under UBM are prone to harbor causative

Indexed as

CYP1B1 gene variantsmicrocatheter-assisted trabeculotomyprimary congenital glaucoma

Identifiers

PMID42211217
PMCPMC13213182

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.