Evidence map›Paper›PMID 42211200›Full record

ArticleInternational journal of ophthalmology2026

Association between choroidal thickness and primary open angle glaucoma in highly myopic eyes.

Pei-Yao Jin, Min Tang, Min-Wen Zhou, Ying Fan, Yu-Ye Ling, Jian-Feng Zhu, Hai-Dong Zou, Jiang-Nan He, Wen-Wen Xue

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Article in International journal of ophthalmology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Pei-Yao JinDepartment of Ophthalmology, Shanghai Eye Disease Prevention and Treatment Center, Shanghai Eye Hospital, School of Medicine, Tongji University, Shanghai 200040, China.
Min TangDepartment of Ophthalmology, Shanghai General Hospital (Shanghai First People's Hospital), Shanghai Jiao Tong University School of Medicine, Shanghai 200080, China.
Min-Wen ZhouDepartment of Ophthalmology, Shanghai General Hospital (Shanghai First People's Hospital), Shanghai Jiao Tong University School of Medicine, Shanghai 200080, China.
Ying FanDepartment of Ophthalmology, Shanghai General Hospital (Shanghai First People's Hospital), Shanghai Jiao Tong University School of Medicine, Shanghai 200080, China.
Yu-Ye LingJohn Hopcroft Center for Computer Science, Shanghai Jiao Tong University, Shanghai 200240, China.
Jian-Feng ZhuDepartment of Preventative Ophthalmology, Shanghai Eye Disease Prevention and Treatment Center, Shanghai Eye Hospital, Shanghai 200040, China.
Hai-Dong ZouDepartment of Ophthalmology, Shanghai Eye Disease Prevention and Treatment Center, Shanghai Eye Hospital, School of Medicine, Tongji University, Shanghai 200040, China.
Jiang-Nan HeDepartment of Preventative Ophthalmology, Shanghai Eye Disease Prevention and Treatment Center, Shanghai Eye Hospital, Shanghai 200040, China.
Wen-Wen XueDepartment of Ophthalmology, Shanghai Eye Disease Prevention and Treatment Center, Shanghai Eye Hospital, School of Medicine, Tongji University, Shanghai 200040, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo investigate the relationship between choroidal thickness (CT) and primary open angle glaucoma (POAG) in highly myopic eyes across different categories of myopic atrophic maculopathy (MAM).

methodsThis observational analytical case-control study enrolled highly myopic patients. All participants underwent comprehensive ophthalmic examinations. CT was measured in peripapillary and macular regions using optical coherence tomography (OCT). Each eye was classified for POAG status and MAM category. Stepwise logistic regression was performed to identify factors independently associated with POAG.

resultsAmong 248 highly myopic subjects, 37 (18 males, mean age 68.25±7.16y) had POAG (25 bilateral, 12 unilateral) and 211 (97 males, mean age 67.09±7.63y) were non-glaucomatous. Age and sex did not differ significantly between groups (both

conclusionIncreased macular CT is independently associated with POAG in highly myopic eyes with diffuse chorioretinal atrophy. This implies distinct pathogenic mechanisms underlying POAG development across different MAM categories in high myopia.

Indexed as

choroidal thicknessglaucomahigh myopiamyopic atrophic maculopathyprimary open angle glaucoma

Identifiers

PMID42211200
PMCPMC13213205

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.