ArticleiScience2026
PGR-mediated transcriptome identifies SOX9 as a critical regulator of progesterone production in human ovulatory follicles.
Article in iScience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
6 authors.
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Abstract
Despite the widespread use of progesterone or progesterone receptor (PGR) blockers as contraceptives, the complete set of PGR-regulated genes and their roles in human ovulatory follicles remain unidentified. Here, we identified the PGR-regulated transcriptome, revealing numerous genes involved in metabolism, steroidogenesis, signaling activation, cell cycle regulation, and transcriptional control during ovulation using integrative omics and a primary human granulosa cell model that recapitulates the
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