Evidence map›Paper›PMID 42211113›Full record

ArticleiScience2026

Phospho-JNK agonists show promising effects for the treatment of hepatocellular carcinoma.

Woonghee Kim, Han Jin, Peipei Miao, Mehmet Ozcan, Xinmeng Liao, Mengzhen Li, Shazia Iqbal, Jihad Sebhaoui, Sajda Ashraf, Burcu Belmen and 6 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in iScience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Woonghee KimScience for Life Laboratory, KTH - Royal Institute of Technology, 17165 Stockholm, Sweden.
Han JinScience for Life Laboratory, KTH - Royal Institute of Technology, 17165 Stockholm, Sweden.
Peipei MiaoTianjian Laboratory of Advanced Biomedical Sciences, Academy of Medical Sciences, Laboratory Animal Center, State Key Laboratory of Esophageal Cancer Prevention & Treatment, Zhengzhou University, Zhengzhou 450052, P.R. China.
Mehmet OzcanFaculty of Medicine, Zonguldak Bulent Ecevit University, Zonguldak 67600, Turkiye.
Xinmeng LiaoScience for Life Laboratory, KTH - Royal Institute of Technology, 17165 Stockholm, Sweden.
Mengzhen LiScience for Life Laboratory, KTH - Royal Institute of Technology, 17165 Stockholm, Sweden.
Shazia IqbalTrustlife Labs Drug Research & Development Center, Istanbul 34774, Turkiye.
Jihad SebhaouiTrustlife Labs Drug Research & Development Center, Istanbul 34774, Turkiye.
Sajda AshrafTrustlife Labs Drug Research & Development Center, Istanbul 34774, Turkiye.
Burcu BelmenTrustlife Labs Drug Research & Development Center, Istanbul 34774, Turkiye.
Hasan TurkezDepartment of Medical Biology, Faculty of Medicine, Atatürk University, Erzurum 25030, Turkey.
Jan BorenDepartment of Molecular and Clinical Medicine, University of Gothenburg, Sahlgrenska University Hospital, 41390 Gothenburg, Sweden.
Mathias UhlenScience for Life Laboratory, KTH - Royal Institute of Technology, 17165 Stockholm, Sweden.
Xiaojing ShiTianjian Laboratory of Advanced Biomedical Sciences, Academy of Medical Sciences, Laboratory Animal Center, State Key Laboratory of Esophageal Cancer Prevention & Treatment, Zhengzhou University, Zhengzhou 450052, P.R. China.
Cheng ZhangScience for Life Laboratory, KTH - Royal Institute of Technology, 17165 Stockholm, Sweden.
Adil MardinogluScience for Life Laboratory, KTH - Royal Institute of Technology, 17165 Stockholm, Sweden.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hepatocellular carcinoma (HCC) remains difficult to treat due to its limited targets. Hence, we introduced phosphorylated c-Jun

Indexed as

Biological sciences

Identifiers

PMID42211113
PMCPMC13214269

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.