Novel approach to sacroiliac joint pain: Preliminary cadaveric and in-silico analysis of safety and feasibility of X-ray-guided high-intensity focused ultrasound ablation.

Eric Miller, Michael Gofeld, Brian Skoglind, Arik Hananel, Suzanne Leblang, Jean-Francois Aubry, Lynn Kohan

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Article in Interventional pain medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

7 authors.

Eric MillerFUSMobile, 6120 Windward Pkwy, STE 210, Alpharetta, GA, 30005, USA.

Michael GofeldUnika Medical Centre, 240 Duncan Mill Road Unit 800, North York, M3B 3S6, Canada.

Brian SkoglindFUSMobile, 6120 Windward Pkwy, STE 210, Alpharetta, GA, 30005, USA.

Arik HananelFUSMobile, 6120 Windward Pkwy, STE 210, Alpharetta, GA, 30005, USA.

Suzanne LeblangFocused Ultrasound Foundation, 1230 Cedars Court Suite 206, Charlottesville, VA, USA, 22903.

Jean-Francois AubryPhysics for Medicine Paris, INSERM U1273, CNRS UMR 8063, ESPCI Paris, PSL University, 10 rue d'Oradour-sur-Glane, 75015, PARIS, France.

Lynn KohanUniversity of Virginia, 545 Ray C. Hunt Drive, Charlottesville, VA, 22903, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Current treatment modalities for chronic sacroiliac joint (SIJ) pain each have advantages and limitations. High-intensity focused ultrasound (HIFU) is a novel, non-invasive tool which produces highly localized thermal ablation using common imaging platforms such as magnetic resonance imaging (MRI), ultrasound, and fluoroscopy. Regulators have approved Fluoroscopy- or X-ray-guided HIFU (XRgHIFU) in the USA, EU, UK, and Canada. Objectives: This study evaluates XRgHIFU's initial safety and feasibility as a non-invasive alternative to RFA for chronic SIJ pain. Methods: In a cadaveric model, thermocouples were implanted in targets along the lateral sacral crest and 1 cm into the foramen. The targets were then sonicated and temperature was recorded.In an Results: The cadaveric and Conclusion: This study supports the safety and feasibility of XRgHIFU for SIJ pain.

Indexed as

Back painChronic painHigh-intensity focused ultrasound ablationPeripheral nerve ablationSacroiliac jointSacroiliitis

Identifiers

PMID42211071

DOI10.1016/j.inpm.2026.100767

PMCPMC13213274

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.