Quantitative longitudinal photoacoustic imaging of vascular oxygenation for therapy response monitoring in Non-Hodgkin lymphoma.

Jing Shi, Ying Fan, Jie Mi, Qianping Mao, Yan Huang, Dean Ta, Ting Feng, Lin Chen

Abstract read

In one paragraph

Article in Photoacoustics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jing ShiDepartment of Ultrsound, Huadong Hospital Affiliated to Fudan University, Shanghai 200040, China.

Ying FanCollege of Biomedical Engineering, Fudan University, Shanghai 200433, China.

Jie MiCollege of Biomedical Engineering, Fudan University, Shanghai 200433, China.

Qianping MaoCollege of Biomedical Engineering, Fudan University, Shanghai 200433, China.

Yan HuangDepartment of Ultrsound, Huadong Hospital Affiliated to Fudan University, Shanghai 200040, China.

Dean TaCollege of Biomedical Engineering, Fudan University, Shanghai 200433, China.

Ting FengCollege of Biomedical Engineering, Fudan University, Shanghai 200433, China.

Lin ChenDepartment of Ultrsound, Huadong Hospital Affiliated to Fudan University, Shanghai 200040, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Non-Hodgkin lymphoma (NHL) is clinically heterogeneous and lacks practical tools for repeated, noninvasive monitoring of response. We performed longitudinal photoacoustic imaging (PAI) at five time points in NHL xenografts to quantify Hb, HbO2, HbT, and mSO2, with endpoint histologic and serum validation. Untreated tumors exhibited a natural progression characterized by a progressive decline in mSO2. While Cyclophosphamide (CTX) slowed growth, it induced earlier alterations in oxygenation: mSO2 was higher in the CTX group on Day 7 (

Indexed as

HypoxiaNon-Hodgkin lymphomaPhotoacoustic imagingTherapeutic responseTumor vasculature remodeling

Identifiers

PMID42211050

DOI10.1016/j.pacs.2026.100835

PMCPMC13213287

What OpenQuestion holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.