SynthesisBJU international2026
Micro- and nanoplastics in the human genitourinary system: oncological impact - a systematic review.
Synthesis in BJU international, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Surrogacy of intermediate clinical endpoints for overall survival in BCG-naïve high-risk non-muscle-invasive bladder cancer.World journal of urology · 2026Observational
- [Microplastic and male urogenital health: current evidence and clinical implications].Urologie (Heidelberg, Germany) · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo systematically assess the prevalence, distribution, and quantitative burden of micro- and nanoplastics (MNPs) in human tissues of the urinary tract and male reproductive organs, with particular attention to their potential oncological implications.
methodsThis systematic review was conducted in accordance with Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. A systematic search of PubMed, Embase, and Scopus was performed to identify human observational studies reporting detection and/or quantification of MNPs in the urinary tract and male reproductive organs. Risk of bias was assessed in the included studies.
resultsA total of 14 cross-sectional human studies were included. MNPs were detected across all investigated tissues, including the kidney, prostate, testis, penis, ureter, and, incidentally, the urinary bladder. All studies comparing malignant and adjacent non-malignant tissues (kidney, prostate, and penis) consistently reported significantly higher microplastic concentrations, particle counts or greater polymer diversity in tumour tissue. Considerable heterogeneity was observed across studies with respect to analytical techniques, digestion protocols, and reporting metrics.
conclusionsMicro- and nanoplastics are widely present in tissues of the urinary tract and male reproductive system and show consistent enrichment in urological malignancies compared with adjacent non-malignant tissue, suggesting potential oncological relevance. Substantial methodological heterogeneity currently limits comparability across studies, underscoring the need for standardised analytical approaches to advance research in this field.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.