ArticleElectrophoresis2026
Development and Evaluation of a Novel Microhaplotype Panel for DNA Mixture and Kinship Analysis.
Article in Electrophoresis, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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14 authors.
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Abstract
Microhaplotypes (MHs), together with the development of next-generation sequencing (NGS), hold great promise for forensic genetics, particularly for mixture interpretation and kinship analysis. In this study, we performed genome-wide screening for new MH markers composed of two or more variants (InDels or single nucleotide polymorphism [SNP]) within 300 bp, based on the Chinese Southern Han (CHS) population from the 1000 Genomes Project (1KG). We developed a 31-plex MH panel specifically for the Chinese Han population, consisting of six MHs and 25 compound markers. The panel demonstrated high polymorphism, with an average effective number of alleles (A
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