Evidence map›Paper›PMID 42210444›Full record

ReviewInternational journal of retina and vitreous2026

Utility of artificial intelligence for the diagnosis, prognosis, and management of central serous chorioretinopathy: a narrative review.

José Ignacio Fernández-Vigo, Alicia Valverde-Megías, Bárbara Burgos-Blasco, José Joaquim de Moura Ramos, Fernando Ly-Yang

Abstract readReview
In one paragraph

Review in International journal of retina and vitreous, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

José Ignacio Fernández-VigoDepartment of Ophthalmology, Hospital Clínico San Carlos, San Carlos Health Research Institute (IdISSC), Profesor Martín Lagos s/n, Madrid, 28040, Spain. jfvigo@hotmail.com.ORCID http://orcid.org/0000-0001-8745-3464
Alicia Valverde-MegíasDepartment of Ophthalmology, Hospital Clínico San Carlos, San Carlos Health Research Institute (IdISSC), Profesor Martín Lagos s/n, Madrid, 28040, Spain.
Bárbara Burgos-BlascoDepartment of Ophthalmology, Hospital Clínico San Carlos, San Carlos Health Research Institute (IdISSC), Profesor Martín Lagos s/n, Madrid, 28040, Spain.
José Joaquim de Moura RamosVARPA Research Group, Instituto de Investigación Biomédica de A Coruña (INIBIC), Universidad da Coruña, A Coruña, Spain.
Fernando Ly-YangDepartment of Ophthalmology, Birmingham and Midland Eye Centre, Sandwell and West Birmingham Hospital, NHS Trust, Birmingham, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Central serous chorioretinopathy (CSC) represents a significant cause of visual impairment, particularly in working-age individuals. Despite advances in multimodal imaging and evidence supporting photodynamic therapy (PDT) as the mainstay of chronic CSC, current clinical workflows are still affected by variability in image interpretation, manual quantification, and individualized treatment selection. This narrative review investigates the utility of Artificial Intelligence (AI) in improving the diagnosis, prognosis, and management of CSC. AI-based image analysis, including Optical Coherence Tomography (OCT), Optical Coherence Tomography Angiography (OCTA), and Fundus Fluorescein Angiography (FFA), has demonstrated high diagnostic accuracy across selected datasets and the ability to identify relevant biomarkers, thereby improving efficiency and consistency. Machine learning models demonstrate promising predictive power for subretinal fluid absorption, visual acuity outcomes, and disease recurrence, and identify critical prognostic factors. While emerging, AI-guided treatment strategies hold promise for personalized therapy, particularly for optimizing PDT, laser-based interventions, and follow-up strategies. The integration of AI into clinical decision-making workflows may elevate diagnostic capabilities, especially for non-specialists, and reduce clinical workload. However, the widespread implementation of AI in CSC faces notable challenges, including dataset bias, limited external validation, insufficient representation of differential diagnoses, regulatory complexities, and ethical considerations pertaining to transparency and equitable access. Future directions emphasize integrating multimodal data, fostering global collaborative efforts, and developing robust, generalizable AI models to fully realize AI's potential to enhance patient care and optimize healthcare delivery for CSC.

Indexed as

Artificial intelligenceBiomarkersCentral serous chorioretinopathyMachine learningPachychoroid diseaseTreatment strategies

Identifiers

PMID42210444
PMCPMC13411760

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.