Evidence map›Paper›PMID 42210430›Full record

ArticleTrials2026

Effects of device-based and manual sensory acuity training on nonspecific chronic low back pain: a three-arm randomized controlled trial protocol.

Ayse Gurluk, Pınar Kaya Saribas, Gokhan Ozkocak, Devrim Tarakci, Elif Hocaoglu

Registry-linked trialAbstract readClinical Trial Protocol
In one paragraph

Article in Trials, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07277803 (Effects of Device-Based and Manual Sensory Acuity Training on Chronic Low Back Pain), which is not on this map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07277803 nanot yet recruitingnot on this map

Effects of Device-Based and Manual Sensory Acuity Training on Chronic Low Back Pain: A Three-Arm Randomized Controlled Trial Protocol

TypeinterventionalSponsorMedipol UniversityRan2026 to 2027Enrolled66ConditionsLow Back PainArmsTechnology-Based Sensory Acuity Training Group (T-SATG), Control Group (CG), Manual Sensory Acuity Training Group (M-SATG)
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ayse GurlukDepartment of Physiotherapy and Rehabilitation, Institute of Health Sciences, Istanbul Medipol University, Istanbul, Turkey. ayse.gurluk@std.medipol.edu.tr.ORCID http://orcid.org/0000-0001-8984-5218
Pınar Kaya SaribasDepartment of Physiotherapy and Rehabilitation, Faculty of Health Sciences, Istanbul Medipol University, Istanbul, Turkey.ORCID http://orcid.org/0000-0002-7611-0527
Gokhan OzkocakDepartment of Physical Medicine and Rehabilitation, Medipol Acıbadem Regional Hospital, Istanbul, Turkey.ORCID http://orcid.org/0000-0003-3174-5630
Devrim TarakciDepartment of Physiotherapy and Rehabilitation, Faculty of Health Sciences, Istanbul Medipol University, Istanbul, Turkey.ORCID http://orcid.org/0000-0001-9804-368X
Elif HocaogluDepartment of Electrical and Electronic Engineering, Faculty of Engineering and Natural Sciences, Istanbul Medipol University, Istanbul, Turkey.ORCID http://orcid.org/0000-0003-3246-972X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundNonspecific chronic low back pain (NCLBP) is a prevalent and disabling condition often associated with impaired sensory discrimination and altered cortical representation. Sensory acuity training (SAT) has emerged as a promising strategy to target these neurophysiological mechanisms; however, the comparative effectiveness of technology-based versus manual sensory acuity interventions remains unclear. This protocol comprises a three-arm, randomized controlled trial designed to evaluate the effects of technology-based and manual SAT, in addition to conventional physiotherapy, compared with conventional physiotherapy alone, on pain and sensory discrimination performance in individuals with NCLBP.

methodsThis single-blind, three-arm parallel randomized controlled trial will recruit 66 adults with NCLBP (> 3 months). Participants will be randomly allocated (1:1:1) to the technology-based SAT, the manual SAT, or a control group. All participants will also receive 30 min of conventional physiotherapy, three times per week for 4 weeks. A blinded assessor will conduct evaluations at baseline, post-intervention, and follow-up. Primary outcomes include pain intensity measured by the visual analog scale, disability evaluated using the Roland-Morris Disability Questionnaire, manual two-point discrimination testing, and sensory acuity performance assessed through TactiPain parameters. Secondary outcomes include pressure pain threshold, joint position sense, laterality performance, central sensitization levels, fear of movement, pain catastrophizing, lumbar body awareness, and quality of life. DISCUSSION: This trial aims to provide high-quality evidence on whether technology-based SAT offers additional benefits compared with manual SAT or a control intervention. By addressing cortical- and sensory-based mechanisms underlying NCLBP, this study may inform the development of more targeted rehabilitation strategies, contribute to clinical decision-making, and guide future research on technology-assisted approaches in musculoskeletal pain rehabilitation.

trial registrationClinicalTrials.gov NCT07277803. Registered on December 2025.

Indexed as

Chronic PainLow Back PainPhysical Therapy ModalitiesAdultDisability EvaluationFemaleHumansMaleMiddle AgedPain MeasurementPain PerceptionPain ThresholdRandomized Controlled Trials as TopicSingle-Blind MethodTime FactorsTreatment OutcomeCentral sensitizationMotor control exerciseNonspecific chronic low back painSensory acuity trainingTechnology-based intervention

Identifiers

PMID42210430
PMCPMC13411384

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.