Evidence map›Paper›PMID 42210165›Full record

ArticleBMC pregnancy and childbirth2026

Adequacy of antenatal care and maternal smoking: impacts on gestational age and birth weight among preterm births in a high-risk referral cohort in Western Iran.

Sajad Nourolahi, Mahnaz Shafieian, Ashraf Direkvand Moghadam

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Article in BMC pregnancy and childbirth, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

3 authors.

Sajad NourolahiDepartment of Pediatrics, School of Medicine, Emam Khomeini Hospital, Ilam University of Medical Sciences, Ilam, Iran.ORCID http://orcid.org/0000-0002-9543-5968
Mahnaz ShafieianInstructor of Midwifery Education, Department of Midwifery, School of Nursing and Midwifery, Ayatollah Taleghani Hospital, Ilam University of Medical Sciences, Ilam, Iran.ORCID http://orcid.org/0000-0002-1548-6571
Ashraf Direkvand MoghadamDepartment of Midwifery, School of Nursing and Midwifery, Ayatollah Taleghani Hospital, Ilam University of Medical Sciences, Ilam, Iran. direkvand-a@medilam.ac.ir.ORCID http://orcid.org/0000-0003-1789-4373

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPreterm birth and low birth weight (LBW) are leading causes of neonatal morbidity and mortality. Adequate antenatal care (ANC) and reducing modifiable maternal risk factors such as smoking are critical, yet evidence from high-risk Middle Eastern populations remains limited.

methodsWe conducted a retrospective cohort study of 451 preterm neonates delivered at a tertiary referral hospital in Ilam, western Iran. ANC adequacy was assessed primarily using the Kessner index and tested against alternative indices. Maternal exposures included smoking, age, hypertension, and diabetes. Logistic regression models assessed associations, with robustness tested through dose-response splines, propensity score weighting, and E-values.

resultsAdequate ANC was protective, reducing odds of earlier gestational age (aOR = 0.52, 95% CI: 0.36-0.76), extremely low birth weight (RRR = 0.28, 95% CI: 0.10-0.76), and LBW overall (aOR = 0.58, 95% CI: 0.39-0.87). Maternal smoking increased risks, more than tripling ELBW (RRR = 3.75, 95% CI: 1.65-8.54) and doubling LBW (aOR = 2.18, 95% CI: 1.20-3.94). Dose-response analysis showed steadily declining LBW risk with increasing ANC utilization, plateauing beyond WHO recommendations. Findings were robust across alternative definitions and sensitivity analyses.

conclusionsAmong preterm births in this high-risk Iranian cohort, adequate ANC was associated with more favorable gestational-age and birth-weight profiles, while maternal smoking increased the severity of prematurity and fetal growth restriction.

Indexed as

Birth WeightGestational AgePremature BirthPrenatal CareSmokingAdultFemaleHumansInfant, Low Birth WeightInfant, NewbornIranPregnancyRetrospective StudiesRisk FactorsAntenatal care adequacyIranlow birth weightmaternal smokingpreterm birth

Identifiers

PMID42210165
PMCPMC13411508

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