Evidence map›Paper›PMID 42210163›Full record

ArticleBMC pregnancy and childbirth2026

Maternal and fetal outcomes in patients with congenital heart disease associated with pulmonary arterial hypertension in high-altitude areas: a retrospective cohort study.

Xiang-Ting Lu, Xue-Rong Chen, Qing Jin, Yun-Yan Xu, Pei-Yun Jin, Yi-Bing Lu, Hai-Long Dai

Abstract read
In one paragraph

Article in BMC pregnancy and childbirth, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Xiang-Ting LuDepartment of Cardiology, Clinical Medicine Center, Key Laboratory for Cardiovascular Disease of Yunnan Province, Yan'an Affiliated Hospital of Kunming Medical University, 245 of east Renming road, Kunming, 650051, China.
Xue-Rong ChenDepartment of Obstetrics, Yan'an Affiliated Hospital of Kunming Medical University, Kunming, 650051, China.
Qing JinDepartment of Obstetrics, Yan'an Affiliated Hospital of Kunming Medical University, Kunming, 650051, China.
Yun-Yan XuDepartment of Cardiology, Clinical Medicine Center, Key Laboratory for Cardiovascular Disease of Yunnan Province, Yan'an Affiliated Hospital of Kunming Medical University, 245 of east Renming road, Kunming, 650051, China.
Pei-Yun JinDepartment of Cardiology, Clinical Medicine Center, Key Laboratory for Cardiovascular Disease of Yunnan Province, Yan'an Affiliated Hospital of Kunming Medical University, 245 of east Renming road, Kunming, 650051, China.
Yi-Bing LuDepartment of Cardiology, Clinical Medicine Center, Key Laboratory for Cardiovascular Disease of Yunnan Province, Yan'an Affiliated Hospital of Kunming Medical University, 245 of east Renming road, Kunming, 650051, China.
Hai-Long DaiDepartment of Cardiology, Clinical Medicine Center, Key Laboratory for Cardiovascular Disease of Yunnan Province, Yan'an Affiliated Hospital of Kunming Medical University, 245 of east Renming road, Kunming, 650051, China. dhlkm@qq.com.

Funding

Innovation Team of Yunnan Province 202505AS350027Key R&D Program of Yunnan Province 202503CL100071National Natural Science Foundation of China 82060018the Noncommunicable Chronic Diseases-National Science and Technology Major Project 2024ZD0526700Yunnan Fundamental Research Projects 202301AY070001-300, 202405AJ310005-17
6 · The paper itself

Abstract

objectivesPulmonary arterial hypertension associated with congenital heart disease (CHD-PAH) increases maternal and fetal risk. This study aimed to analyze maternal and fetal outcomes in patients with CHD-PAH in high-altitude areas.

methodsThe pregnant women with CHD were analyzed retrospectively from 2012 to 2022. Pulmonary artery systolic pressure (PASP) was estimated by echocardiography. Patients were categorized into four groups: no PAH (PASP < 40 mmHg), mild (40 mmHg≤PASP < 50 mmHg), moderate (50 mmHg≤PASP < 70 mmHg) and severe PAH (PASP ≥ 70 mmHg).

results429 pregnant women were included in this study, 187 with no PAH, 102 with mild PAH, 79 with moderate PAH, 61 with severe PAH. The severe PAH group had the highest proportions of NYHA functional classes III/IV, SpO

conclusionsThe level of PASP, NT-proBNP, and NYHA function class, BMI may be useful in risk stratification in pregnancy with CHD-PAH in high-altitude areas.

Indexed as

AltitudeHeart Defects, CongenitalPregnancy Complications, CardiovascularPregnancy OutcomePulmonary Arterial HypertensionAdultChinaEchocardiographyFemaleHumansInfant, NewbornNatriuretic Peptide, BrainPeptide FragmentsPregnancyPremature BirthRetrospective StudiesNatriuretic Peptide, BrainPeptide Fragmentspro-brain natriuretic peptide (1-76)Congenital heart diseaseHigh-altitude areasMaternal and fetal outcomesPregnancyPulmonary arterial hypertension

Identifiers

PMID42210163
PMCPMC13411844

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.