ArticleBMC ophthalmology2026
Long-term impact of scleral contact lens use on endothelial cell density in patients with moderate to advanced keratoconus.
Article in BMC ophthalmology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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5 authors.
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Abstract
backgroundWe investigated the effect of long-term use of scleral contact lens (SL) on corneal endothelial parameters in patients with keratoconus (KC).
methodsSpecular microscopy (Konan Cell Check SL, Hyogo, Japan) imaging was performed on healthy subjects (control group) and patients with KC (KC group) who were long-term SL wearers using the center method. Specular microscopy measurements were taken for both the groups before and after SL use.
resultsThe mean duration of SL use in the KC group was 5 ± 2 years. No significant differences in specular microscopy parameters were noted between the first and last examinations of the control and KC groups.
conclusionCorneal endothelial parameters were not affected in long-term SL wearers when the recommended fitting and usage practices were followed, suggesting that SL use is well tolerated by the corneal endothelium. However, further research involving larger cohorts is essential to confirm the long-term safety of SL use.
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