Evidence map›Paper›PMID 42210126›Full record

ArticleBMC medical research methodology2026

Clustering methods for categorical time series and sequences : a scoping review.

Ottavio Khalifa, Alan Balendran, Viet-Thi Tran, François Petit

Abstract readScoping Review
In one paragraph

Article in BMC medical research methodology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ottavio KhalifaUniversité Paris Cité, Université Sorbonne Paris Nord, INSERM, INRAE, Centre for Research in Epidemiology and StatisticS (CRESS), Paris, France. ottavio.khalifa@inserm.fr.
Alan BalendranUniversité Paris Cité, Université Sorbonne Paris Nord, INSERM, INRAE, Centre for Research in Epidemiology and StatisticS (CRESS), Paris, France.
Viet-Thi TranUniversité Paris Cité, Université Sorbonne Paris Nord, INSERM, INRAE, Centre for Research in Epidemiology and StatisticS (CRESS), Paris, France.
François PetitUniversité Paris Cité, Université Sorbonne Paris Nord, INSERM, INRAE, Centre for Research in Epidemiology and StatisticS (CRESS), Paris, France.

Funding

Agence Nationale de la Recherche, France ANR-22-CPJ1-0047-01.
6 · The paper itself

Abstract

objectiveTo provide an overview of clustering methods for categorical time series (CTS), a data structure common in epidemiology, sociology, biology, and marketing, and to support method selection according to data characteristics. MATERIALS AND

methodsWe searched PubMed (via MEDLINE), Web of Science, and Google Scholar up to November 2024 for articles proposing and evaluating CTS clustering techniques. Methods were classified into three families-distance-based, feature-based, and model-based-and assessed for their ability to address challenges such as variable sequence length, multivariate data, continuous time, missing data, covariates, and large data volumes.

resultsOf 14,607 records retrieved, 124 articles describing 129 methods were included. Distance-based approaches, especially those using Optimal Matching, were most common, with 56 methods. We found 28 model-based methods, which covered a broader range of complex data structures such as multivariate data, continuous time and time-invariant covariates. We recorded 45 feature-based approaches, which were on average more scalable but less flexible. Fewer than half of the methods provided public implementations. A searchable Web application ( https://cts-clustering-scoping-review-7sxqj3sameqvmwkvnzfynz.streamlit.app/ ) was developed to support method selection. DISCUSSION: CTS clustering methods are highly heterogeneous in assumptions, capabilities, and scalability. Distance-based approaches dominate, but model-based methods offer richer modeling potential, while feature-based ones emphasize performance at the cost of flexibility.

conclusionThis review highlights methodological diversity and gaps in CTS clustering. The proposed typology and Web application aim to help researchers choose appropriate methods to choose appropriate methods for their data.

Indexed as

Cluster AnalysisAlgorithmsCare TrajectoriesCategoricalClusteringReviewSequence AnalysisTime Series

Identifiers

PMID42210126
PMCPMC13217966

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.