Evidence map›Paper›PMID 42209881›Full record

ArticleJournal of neurology2026

Artificial intelligence for gait and balance in neurological disorders: a scoping review of clinical applications and technologies.

C Pegorini, D Cattaneo, M Meotti, F Baglio, A Mannini, C Cordani, E Gervasoni

Abstract readScoping Review
PubMed Publisher
In one paragraph

Article in Journal of neurology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

C PegoriniIRCCS Fondazione Don Carlo Gnocchi ETS, Via Capecelatro 66, 20148, Milan, Italy.ORCID http://orcid.org/0009-0001-0662-0388
D CattaneoIRCCS Fondazione Don Carlo Gnocchi ETS, Via Capecelatro 66, 20148, Milan, Italy. dcattaneo@dongnocchi.it.ORCID http://orcid.org/0000-0003-4251-1856
M MeottiIRCCS Fondazione Don Carlo Gnocchi ETS, Via Capecelatro 66, 20148, Milan, Italy.
F BaglioIRCCS Fondazione Don Carlo Gnocchi ETS, Via Capecelatro 66, 20148, Milan, Italy.ORCID http://orcid.org/0000-0002-6145-5274
A ManniniIRCCS Fondazione Don Carlo Gnocchi ETS, Florence, Italy.ORCID http://orcid.org/0000-0003-0760-052X
C CordaniIRCCS Galeazzi-Sant'Ambrogio Hospital, Milan, Italy.ORCID http://orcid.org/0000-0002-9014-7887
E GervasoniIRCCS Fondazione Don Carlo Gnocchi ETS, Via Capecelatro 66, 20148, Milan, Italy.ORCID http://orcid.org/0000-0002-6057-591X

Funding

Ministero della Salute PNC0000007Ministero della Salute RC 2026
6 · The paper itself

Abstract

backgroundArtificial intelligence (AI) has rapidly emerged within healthcare systems and neurological rehabilitation with the potential to revolutionize clinical decision-making and therapeutic strategies. However, a comprehensive understanding of how AI is currently applied to gait and balance rehabilitation in stroke, Parkinson's disease (PD), and multiple sclerosis (MS) is still lacking.

objectiveTo map the current use of AI in neurological rehabilitation, focusing on clinical purposes, geographical distribution, and applied technologies for gait and balance rehabilitation.

methodsFollowing the PRISMA-ScR statement, we conducted a literature search through MEDLINE, Cochrane CENTRAL, EMBASE, and Google Scholar up to July 2025 to identify studies applying AI-based methods to gait and balance outcomes in adults with stroke, PD, or MS. Study characteristics, AI methods, validation strategies, clinical purpose, and motor outcomes were extracted and synthesized narratively.

resultsEighteen studies published from 2009 to 2025 were included. Most studies were conducted in Asia (50%) and involved people with stroke (77.8%). AI was predominantly used for prognostic purposes (72.22%), such as predicting falls, gait recovery, or treatment response and diagnostic applications (33.3%). Machine learning was the most common approach (88.9%) with Random Forest, Support Vector Machine, logistic regression, and eXtreme Gradient Boosting being the most frequently applied algorithms. None of the included studies performed prospective or external validation on independent datasets.

conclusionsThis scoping review provides a comprehensive overview of current AI applications, highlighting promising but still immature approaches in the neurological rehabilitation of gait and balance. However, substantial methodological limitations remain major barriers to clinical translation.

Indexed as

Artificial IntelligenceGaitGait Disorders, NeurologicNervous System DiseasesNeurological RehabilitationPostural BalanceHumansMultiple SclerosisParkinson DiseaseStrokeArtificial intelligenceGaitNervous system diseasesPostural balanceRehabilitation

Identifiers

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.