Evidence map›Paper›PMID 42209860›Full record

ReviewSurgical endoscopy2026

Clinical spotlight review: best practices for the management of colorectal cancer in the emergency and acute care setting.

Patricia Tejedor, Carlos Pastor, Antonio Caycedo-Marulanda, Mark Whiteford, Elisabeth C McLemore, Patricia Sylla, Marylise Boutros, Nawar A Alkhamesi, SAGES Colorectal Committee, Acute Care Surgery Committee

Abstract readReview
PubMed Publisher
In one paragraph

Review in Surgical endoscopy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Patricia TejedorColorectal Surgery Unit, University Hospital Gregorio Marañón, Madrid, Spain.
Carlos PastorDepartment of Surgery, Colorectal Surgery Unit, University Clinic of Navarre, Madrid, Spain.
Antonio Caycedo-MarulandaOrlando Health Colon & Rectal Institute, Orlando, FL, USA.
Mark WhitefordCenter for Advanced SurgeryPC; Director, Colon and Rectal SurgeryAffiliate Professor of Surgery, The Oregon ClinicProvidence Portland Cancer InstituteOregon Health & Science University, Portland, OR, USA.
Elisabeth C McLemoreDepartment of Surgery, Kaiser Permanente Bernard J. Tyson School of Medicine, Kaiser Permanente Medical Center, Los Angeles, CA, USA.
Patricia SyllaSystem Chief, Division of Colon and Rectal Surgery, Mount Sinai Health System, New York, NY, USA.
Marylise BoutrosDepartment of Colorectal Surgery, Clevland Clinic Florida, Weston, FL, USA.
Nawar A AlkhamesiKadlec Regional Medical Center, Elison S. Floyed College of Medicine, Washington State University, Richland, WA, USA. nawar.alkhamesi@wsu.edu.ORCID http://orcid.org/0000-0001-6217-6253
SAGES Colorectal Committee, Acute Care Surgery Committee

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundColorectal cancer (CRC) is a leading cause of cancer mortality, and up to one-third of patients present with obstruction, perforation, or bleeding. Emergency presentation is associated with advanced stage, higher rates of open surgery and stoma formation, and worse survival. This review synthesizes current evidence and provides practical guidance for emergency and acute care management of CRC.

methodsWe conducted a comprehensive search of MEDLINE and EMBASE for English-language studies from 2000 through July 2025, including randomized trials, meta-analyses, and cohort studies. Data were synthesized by members of the SAGES Colorectal and Acute Care Surgery Committees to identify consensus practices and safe strategies across resource settings.

resultsContrast-enhanced CT is the diagnostic cornerstone; endoscopy adds diagnostic and therapeutic value when feasible. For right-sided cancers, oncologic right colectomy with primary anastomosis is generally safe in obstruction and selected perforations; diversion or staged surgery is preferred in unstable or contaminated fields. For left-sided obstruction, options include Hartmann's procedure, resection with primary anastomosis (± diversion), loop colostomy, or self-expandable metal stents (SEMS). SEMS provide effective decompression and enable minimally invasive interval resection with lower stoma rates when available. Perforation requires individualized strategies based on contamination; Hartmann's procedure and subtotal colectomy are commonly employed. In rectal cancer, emergency care should prioritize stabilization, decompression, biopsy, and facilitation of neoadjuvant therapy rather than immediate resection.

conclusionsOptimal emergency CRC care requires rapid diagnosis, oncologic principles, and individualized operative planning. Bridge-to-surgery strategies, selective diversion, and judicious use of minimally invasive techniques can reduce morbidity, expedite oncologic therapy, and improve outcomes.

Indexed as

Colorectal NeoplasmsAcute Care SurgeryColectomyColorectal Surgical ProceduresHumansIntestinal ObstructionSelf Expandable Metallic StentsAcute care surgeryColorectal cancerEmergency surgeryIntestinal perforationLarge-bowel obstructionMinimally invasive surgeryRectal cancer

Identifiers

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.