Evidence map›Paper›PMID 42209691›Full record

Trial reportScientific reports2026

Design, implementation, and evaluation of neonatal abstinence syndrome care management web application: a multimethod study.

Raziyeh Beykmirza, Mohadese Babaie, Elham Eghbali Gharahbolaghm, Arman Give, Maryam Varzeshnejad

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Raziyeh BeykmirzaNursing and Midwifery Care Research Center, School of Nursing and Midwifery, Tehran University of Medical Sciences, Tehran, Iran.ORCID http://orcid.org/0000-0002-5327-1336
Mohadese BabaieNon-communicable Diseases Research Center, Alborz University of Medical Sciences, Karaj, Iran.ORCID http://orcid.org/0000-0002-7154-2793
Elham Eghbali GharahbolaghmDepartment of Pediatric Nursing, Student Research Committee, School of Nursing and Midwifery, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Arman GiveDepartment of Computer Science, Yadegar-e-Imam Khomeini, Shahre Rey Branch, Islamic Azad University, Tehran, Iran.ORCID http://orcid.org/0009-0007-2437-492X
Maryam VarzeshnejadDepartment of Pediatric Nursing, School of Nursing and Midwifery, Shahid Beheshti University of Medical Sciences, Tehran, Iran. m.varzeshnejad@gmail.com.ORCID http://orcid.org/0000-0002-1016-248X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The Finnegan scoring tool is the clinical standard for assessing neonatal abstinence syndrome (NAS), but manual calculation and documentation pose challenges. Digital decision-support systems may enhance accuracy, streamline workflows, and improve therapeutic interventions. This study aimed to design, implement, and evaluate a neonatal abstinence syndrome decision support web application and record the care management based on the Finnegan scoring system. This study was conducted using a multi-method approach and included design, implementation, and evaluation phases. In the system design phase, the waterfall model was used. The second and third phases of the study, implementation and evaluation, were conducted as a randomized controlled trial. A total of 142 infants diagnosed with neonatal abstinence syndrome were randomly divided into two groups: the intervention group, which used a web-based application that automatically calculates the Finnegan score and provides therapeutic advice, and the control group, which relied on manual calculation and routine care. Data were collected from birth to 5 days post-natal age. Although Finnegan scores decreased significantly over time in both groups (p < 0.001), the between-group comparison showed no statistically significant difference in mean score reduction (p = 0.18). However, clinically meaningful differences were observed: documentation adherence was significantly higher in the intervention group (96.7% vs. 91.4%, p < 0.001), and the frequency of pharmacological interventions was 36% lower in the intervention group compared to controls (p < 0.001). User satisfaction scored ≥ 3.5/5 across all domains. The NAS care management web application improved documentation accuracy, reduced medication interventions, and demonstrated high user satisfaction. It offers a clinically viable tool to standardize and enhance NAS care in neonatal settings.

Indexed as

Decision Support Systems, ClinicalInternetNeonatal Abstinence SyndromeHumansInfant, NewbornFinnegan’s ScoringNeonatal abstinence syndromeNeonatesWeb application

Identifiers

PMID42209691
PMCPMC13490485

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.