Evidence map›Paper›PMID 42209667›Full record

Trial reportScientific reports2026

Quantitative assessment of inspiratory loading on postprandial glycemia and metabolic response in healthy adults.

Dongwook Yeo, Jesse C Schwartz, Jinkyung Cho, Bruce D Johnson, Chul-Ho Kim

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Dongwook YeoDepartment of Cardiovascular Diseases, Mayo Clinic, Rochester, MN, 55905, USA.
Jesse C SchwartzDepartment of Cardiovascular Diseases, Mayo Clinic, Rochester, MN, 55905, USA.
Jinkyung ChoDepartment of Cardiovascular Diseases, Mayo Clinic, Rochester, MN, 55905, USA.
Bruce D JohnsonDepartment of Cardiovascular Diseases, Mayo Clinic, Rochester, MN, 55905, USA.
Chul-Ho KimDepartment of Cardiovascular Diseases, Mayo Clinic, Rochester, MN, 55905, USA. Kim.Chulho@mayo.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Postprandial blood glucose (BG) regulation is a central determinant of metabolic health and cardiometabolic risk. While conventional exercise effectively lowers postprandial BG, alternative approaches that impose minimal musculoskeletal load remain underexplored. Inspiratory loading (IL) -repeated inspirations against graded resistance -selectively activates oxidative respiratory muscles. However, its real-time metabolic and mechanical demands and their influence on systemic glucose regulation have not been quantified. In this study, we quantitatively characterized the concurrent metabolic and mechanical responses to graded IL and examined their acute effects on postprandial BG in healthy adults. Six participants completed three randomized IL sessions-SHAM (no resistance), MOD (~ 40% maximal inspiratory pressure, MIP), and HIGH (~ 60% MIP)-separated by ≥ 72-h washouts. After fasting measurements, participants ingested 45 g of D-glucose followed by a 30-min IL protocol (6 × 4-min bouts with 1-min rest). Oxygen consumption (VO

Indexed as

Blood GlucoseInhalationPostprandial PeriodAdultFemaleHealthy VolunteersHeart RateHumansMaleOxygen ConsumptionRespiratory MusclesYoung AdultBlood Glucose

Identifiers

PMID42209667
PMCPMC13462701

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.