Evidence map›Paper›PMID 42209492›Full record

ArticleNature communications2026

Reference-point dependent reinforcement learning in humans and rats.

Lachlan A Ferguson, Magdalena Soukupova, Sébastien Bouret, Stefano Palminteri, Shauna L Parkes

Abstract read
In one paragraph

Article in Nature communications, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Lachlan A Ferguson *Univ. Bordeaux, CNRS, INCIA, UMR 5287, Bordeaux, France.ORCID http://orcid.org/0000-0003-4048-4137
Magdalena Soukupova *Laboratoire des Neurosciences Cognitives et Computationnelles, Institut National de la Santé et de la Recherche Médicale, Paris, France.ORCID http://orcid.org/0000-0001-6792-0619
Sébastien BouretMotivation Brain and Behaviour team, ICM, Paris, France.
Stefano PalminteriLaboratoire des Neurosciences Cognitives et Computationnelles, Institut National de la Santé et de la Recherche Médicale, Paris, France. stefano.palminteri@gmail.com.ORCID http://orcid.org/0000-0001-5768-6646
Shauna L ParkesUniv. Bordeaux, CNRS, INCIA, UMR 5287, Bordeaux, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Rewards and punishments in reinforcement learning are encoded in both absolute and relative manners. Reference-point dependence, a valuation bias shared by adaptation-level and prospect theories, is often proposed as the computational mechanism underlying relative value encoding. However, the extent to which these behavioural and computational mechanisms are conserved across species remains to be fully understood. We therefore designed parallel reinforcement learning tasks in humans and rats to examine reference-point dependence across species. Behavioural analyses showed robust relative value encoding in both species, and computational modelling confirmed that reference-point dependence reliably accounts for behaviour in humans and rats. Despite these major similarities between species, some differences in behavioural and modelling parameters were observed. Overall, our study demonstrates that relative value encoding is a robust feature of reinforcement learning that is conserved across humans and rats.

Indexed as

LearningReinforcement, PsychologyAdultAnimalsBehavior, AnimalFemaleHumansMalePunishmentRatsReinforcement Machine LearningRewardYoung Adult

Identifiers

PMID42209492
PMCPMC13389395

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.