Evidence map›Paper›PMID 42208959›Full record

ArticlePsychological medicine2026

Factors associated with social functioning by relapse frequency in Japanese outpatients with schizophrenia: the Multicenter Treatment Survey and Assessments for Schizophrenia in Psychiatric Clinics (MUSASI).

Yoshiteru Takekita, Eiichi Katsumoto, Naoto Adachi, Yukihisa Kubota, Koji Edagawa, Takaharu Azekawa, Hitoshi Ueda, Tatsuji Tamura, Seiji Hongo, Eiichiro Goto and 7 more

Abstract readMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Psychological medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

17 authors.

Yoshiteru TakekitaDepartment of Neuropsychiatry, Faculty of Medicine, https://ror.org/001xjdh50Kansai Medical University, Hirakata, Japan.ORCID 0000-0003-2435-4033
Eiichi KatsumotoKatsumoto Mental Clinic, Osaka, Japan.
Naoto AdachiAdachi Mental Clinic, Sapporo, Japan.
Yukihisa KubotaChuokoen Clinic, Fuji, Japan.
Koji EdagawaEdagawa Clinic, Tokushima, Japan.
Takaharu AzekawaShioiri Mental Clinic, Yokosuka, Japan.
Hitoshi UedaMorioka Cocoro Clinic, Morioka, Japan.
Tatsuji TamuraTamura Mental Clinic, Hiroshima, Japan.
Seiji HongoNanko Institute of Psychiatry, Shirakawa, Japan.
Eiichiro GotoShinwado Goto Clinic, Fukuoka, Japan.
Hirohisa HidaHida Clinic, Nagareyama, Japan.
Kazuhira MikiMiki Mental Clinic, Yokohama, Japan.
Chiyo Fujiihttps://ror.org/0254bmq54National Center of Neurology and Psychiatry, Kodaira, Japan.
Koichiro WatanabeDepartment of Neuropsychiatry, https://ror.org/0188yz413Kyorin University School of Medicine, Mitaka, Japan.
Masaki KatoDepartment of Neuropsychiatry, Faculty of Medicine, https://ror.org/001xjdh50Kansai Medical University, Hirakata, Japan.
Norio Yasui-Furukorihttps://ror.org/05k27ay38Department of Psychiatry, Dokkyo Medical University School of Medicine, Mibu, Japan.
Hiroyoshi TakeuchiDepartment of Psychiatry, https://ror.org/01hjzeq58Chiba University Graduate School of Medicine, Chiba, Japan.ORCID 0000-0002-8844-4786

Funding

Japan Society for the Promotion of Science 23K07024
6 · The paper itself

Abstract

backgroundImpaired social functioning substantially affects the quality of life of patients with schizophrenia; however, it remains unclear whether the factors associated with social functioning differ according to relapse frequency. This study aimed to examine the differences in these factors among Japanese outpatients with schizophrenia, stratified by relapse frequency.

methodsThis nationwide cross-sectional study, the Multicenter Treatment Survey and Assessments for Schizophrenia in Psychiatric Clinics (MUSASI), was conducted in 330 psychiatric clinics in Japan between September and October 2023. A total of 10,081 patients diagnosed with schizophrenia-related disorders were analyzed. Patients were categorized as nonrelapsers, low-frequency relapsers (1-2 relapses), or high-frequency relapsers (≥3 relapses). Social functioning was assessed using the Social and Occupational Functioning Assessment Scale, with scores ≥61 defined as high functioning.

resultsThis study included 3,670 nonrelapsers, 4,428 low-frequency relapsers, and 1,983 high-frequency relapsers. Overall, 55.8% (

conclusionsFactors associated with social functioning differed according to relapse frequency, highlighting the need for relapse frequency-based, stratified intervention strategies.

Indexed as

Psychosocial FunctioningSchizophreniaSchizophrenic PsychologySocial InteractionAdultCross-Sectional StudiesFemaleHumansJapanMaleMiddle AgedOutpatientsQuality of LifeRecurrenceoutpatientsrecurrencerelapserisk factorsschizophreniasocial functioning

Identifiers

PMID42208959
PMCPMC13234521

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