Evidence map›Paper›PMID 42207689›Full record

ArticleJournal of the American Chemical Society2026

Employing AC and DC Electrolysis to Modulate Electroenzymatic Pathways for Efficient and Stereoselective H-D Exchange.

Wassim El Housseini, Rokas Gerulskis, Nibedita Behera, Huaijun Guan, Rohit G Jadhav, Zachary A Nguyen, Egor Baiarashov, Michael A Pence, Vamshi Krishna Kamaja, Trevor Larkin and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of the American Chemical Society, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Wassim El HousseiniKummer Institute Center for Resource Sustainability, Missouri University of Science and Technology, Rolla, Missouri 65409, United States.
Rokas GerulskisDepartment of Chemistry, University of Utah, Salt Lake City, Utah 84112, United States.
Nibedita BeheraDepartment of Chemistry, University of Utah, Salt Lake City, Utah 84112, United States.
Huaijun GuanKummer Institute Center for Resource Sustainability, Missouri University of Science and Technology, Rolla, Missouri 65409, United States.
Rohit G JadhavKummer Institute Center for Resource Sustainability, Missouri University of Science and Technology, Rolla, Missouri 65409, United States.ORCID 0000-0001-6377-7253
Zachary A NguyenDepartment of Chemistry, University of Utah, Salt Lake City, Utah 84112, United States.ORCID 0000-0002-1530-4950
Egor BaiarashovKummer Institute Center for Resource Sustainability, Missouri University of Science and Technology, Rolla, Missouri 65409, United States.
Michael A PenceKummer Institute Center for Resource Sustainability, Missouri University of Science and Technology, Rolla, Missouri 65409, United States.
Vamshi Krishna KamajaKummer Institute Center for Resource Sustainability, Missouri University of Science and Technology, Rolla, Missouri 65409, United States.ORCID 0000-0003-4380-8424
Trevor LarkinKummer Institute Center for Resource Sustainability, Missouri University of Science and Technology, Rolla, Missouri 65409, United States.
Long LuoDepartment of Chemistry, University of Utah, Salt Lake City, Utah 84112, United States.ORCID 0000-0001-5771-6892
Shelley D MinteerKummer Institute Center for Resource Sustainability, Missouri University of Science and Technology, Rolla, Missouri 65409, United States.ORCID 0000-0002-5788-2249

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Stereoselective hydrogen isotope exchange (HIE) at chiral centers is an increasingly important strategy for preparing labeled molecules, yet its practical implementation depends on reliable control of nicotinamide cofactor regeneration. Here we introduce a redox-programmable electroenzymatic platform for stereoselective HIE based on electrode-controlled manipulation of the nicotinamide cofactor state. A wired ferredoxin-NADP

Identifiers

PMID42207689
PMCPMC13266969

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.