Evidence map›Paper›PMID 42207659›Full record

SynthesisPsychological bulletin2026

Relationships between cognition and daily functioning in adults with bipolar disorder: A systematic review and multilevel meta-analysis.

Amanda McCleery, Gerhard Stefan Hellemann, Junghee Lee

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in Psychological bulletin, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Amanda McCleeryDepartment of Psychology, Faculty of Arts, University of Manitoba.
Gerhard Stefan HellemannDepartment of Biostatistics, School of Public Health, University of Alabama at Birmingham.
Junghee LeeDepartment of Psychiatry and Behavioral Neurobiology, Heersink School of Medicine, University of Alabama at Birmingham.

Funding

Disrupted Social Preference in Early Psychosis: A Longitudinal Multimodal Neuroimaging StudyR01MH113856 · NIMH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI LEE, JUNGHEE · 2018 to 2022
$2.7M
Cortical Plasticity Across Phase of Illness in SchizophreniaK23MH108829 · NIMH · UNIVERSITY OF IOWA · PI MCCLEERY, AMANDA · 2016 to 2022
$910k
National Institute of Mental Health; National Institutes of HealthNIMH NIH HHS K23 MH108829NIMH NIH HHS R01 MH113856
6 · The paper itself

Abstract

Cognitive impairment is a common, yet underrecognized, feature of bipolar disorder (BD). While cognition has emerged as a contributing factor to poor functioning in BD, previous reviews did not examine the role of cognitive domains (i.e., social cognition, nonsocial cognition) or the role of key potential moderators, including age and sex. A systematic literature search identified studies that included assessments of cognition and functioning in BD (103 reports, 2,200 effect sizes, 9,323 BD participants). Multilevel models tested the association between cognition and functioning, as well as moderation by cognitive domain, functional domain, biological factors, and clinical factors. Better overall cognitive performance was associated with better overall functioning (r = .20, p < .001). In contrast to the schizophrenia literature, nonsocial cognition was more strongly related to functioning (r = .21, p < .001) than social cognition (r = .16, p < .001). The magnitude of the relationship differed across cognitive and functional domains and was moderated by age, sex, clinical factors, and risk of bias. Social and nonsocial cognition make small, but statistically significant, contributions (i.e., 4% variance) to daily functioning in people with BD. This finding supports cognition as a viable treatment target to improve functioning in BD, with appropriate consideration of key moderators. (PsycInfo Database Record (c) 2026 APA, all rights reserved).

Indexed as

Activities of Daily LivingBipolar DisorderCognitionCognitive DysfunctionSocial CognitionAdultFemaleHumansMale

Identifiers

PMID42207659
PMCPMC13313034

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.