Evidence map›Paper›PMID 42207409›Full record

ArticleDigestive diseases and sciences2026

Association Between Toothbrushing Habits and Mucosal Healing in Japanese Patients with Ulcerative Colitis.

Sen Yagi, Shinya Furukawa, Teruki Miyake, Osamu Yoshida, Kazuhiro Tange, Shogo Kitahata, Tomoyuki Ninomiya, Masakazu Hanayama, Seiyuu Suzuki, Naozumi Shibata and 7 more

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Article in Digestive diseases and sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Sen YagiDepartment of Internal Medicine, Saiseikai Imabari Hospital, Imabari, Ehime, 799-1592, Japan.
Shinya FurukawaHealth Services Center, Ehime University, Bunkyo, Matsuyama, Ehime, 790-8577, Japan. furukawa.shinya.mf@ehime-u.ac.jp.ORCID http://orcid.org/0000-0002-0041-7688
Teruki MiyakeDepartment of Gastroenterology and Metabology, Ehime University Graduate School of Medicine, Toon, Ehime, 791-0295, Japan.
Osamu YoshidaDepartment of Gastroenterology and Metabology, Ehime University Graduate School of Medicine, Toon, Ehime, 791-0295, Japan.
Kazuhiro TangeDepartment of Inflammatory Bowel Diseases and Therapeutics, Ehime University Graduate School of Medicine, Toon, Ehime, 791-0295, Japan.
Shogo KitahataDepartment of Gastroenterology, Ehime Prefectural Central Hospital, Matsuyama, Ehime, 790-0024, Japan.
Tomoyuki NinomiyaDepartment of Gastroenterology, Ehime Prefectural Central Hospital, Matsuyama, Ehime, 790-0024, Japan.
Masakazu HanayamaDepartment of Gastroenterology, Matsuyama Shimin Hospital, Matsuyama, Ehime, 790-0067, Japan.
Seiyuu SuzukiDepartment of Gastroenterology, Sumitomo Besshi Hospital, Niihama, Ehime, 792-8543, Japan.
Naozumi ShibataDepartment of Gastroenterology, Ehime Prefectural Niihama Hospital, Niihama, Ehime, 792-0042, Japan.
Hidehiro MurakamiDepartment of Internal Medicine, Saiseikai Matsuyama Hospital, Matsuyama, Ehime, 791-8026, Japan.
Katsuhisa OhashiOHASHI Clinic Participate in Gastro-Enterology and Ano-Proctology, Niihama, Ehime, 792-0856, Japan.
Hideomi TomidaEndoscopy Center, Ehime University Hospital, Toon, Ehime, 791-0295, Japan.
Yasunori YamamotoEndoscopy Center, Ehime University Hospital, Toon, Ehime, 791-0295, Japan.
Eiji TakeshitaDepartment of Inflammatory Bowel Diseases and Therapeutics, Ehime University Graduate School of Medicine, Toon, Ehime, 791-0295, Japan.
Yoshio IkedaEndoscopy Center, Ehime University Hospital, Toon, Ehime, 791-0295, Japan.
Yoichi HiasaDepartment of Gastroenterology and Metabology, Ehime University Graduate School of Medicine, Toon, Ehime, 791-0295, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveEvidence regarding the association between oral environment and the inflammatory bowel disease (IBD), including ulcerative colitis (UC), exists. However, evidence regarding the association between oral health parameters and disease activity of UC is limited. This study aimed to evaluate the association between remaining tooth number and toothbrushing frequency and mucosal healing (MH) in Japanese UC patients.

methodThe study included 275 patients with UC. Information on lifestyle and oral health parameters was collected via self-administered questionnaires. The definition of MH was based on the Mayo endoscopic subscore (MES) of 0.

resultsThe prevalence of MH in this cohort was 24.7%. The distribution of remaining teeth was as follows: 13.1% had 20 or fewer teeth, 32.7% had 20-27 teeth, and 54.2% had 28 teeth. Toothbrushing frequency was 23.6% brushed once or less per day, 46.9% brushed twice per day, and 29.5% brushed three or more times per day. No significant difference was observed between remaining teeth and MH. However, toothbrushing frequency is independently positively associated with MH (adjusted odds ratio: 2.87 [95% CI: 1.19-7.29]; p value for trend = 0.021).

conclusionToothbrushing frequency but not the remaining tooth number might be independently and positively associated with MH in Japanese patients with UC.

Indexed as

Colitis, UlcerativeIntestinal MucosaToothbrushingWound HealingAdultFemaleHumansJapanMaleMiddle AgedPrevalenceSurveys and QuestionnairesMucosal healingToothbrushing habitsUlcerative colitis

Identifiers

PMID42207409
PMCPMC13558442

What OpenQuestion holds

Textmetadata
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.