Evidence map›Paper›PMID 42207321›Full record

ArticleClinical oral investigations2026

Remote assessment of caries, MIH, and plaque on intraoral 3D scan images: Findings from the LIFE Child study.

Nadja Stiller, Jana Schmidt, Christof Meigen, Anne Messerschmidt, Wieland Kiess, Mandy Vogel, Antje Körner, Ellen Schulz-Kornas, Rainer Haak

Abstract read
In one paragraph

Article in Clinical oral investigations, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Reliability and Diagnostic Performance of Digital Versus Clinical Assessment of Oral Hygiene and Gingival Health in Older Community-dwelling Adults.Special care in dentistry : official publication of the American Association of Hospital Dentists, the Academy of Dentistry for the Handicapped, and the American Society for Geriatric Dentistry
    Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Nadja Stiller *Department of Cariology, Endodontology and Periodontology, University of Leipzig, Leipzig, Germany.
Jana Schmidt *Department of Cariology, Endodontology and Periodontology, University of Leipzig, Leipzig, Germany. jana.schmidt@medizin.uni-leipzig.de.
Christof MeigenMedical Faculty, Center for Pediatric Research (CPL), Leipzig University, University Hospital for Children and Adolescents Leipzig, LIFE Child, Leipzig, Germany.
Anne MesserschmidtDepartment of Cariology, Endodontology and Periodontology, University of Leipzig, Leipzig, Germany.
Wieland KiessMedical Faculty, Center for Pediatric Research (CPL), Leipzig University, University Hospital for Children and Adolescents Leipzig, LIFE Child, Leipzig, Germany.
Mandy VogelMedical Faculty, Center for Pediatric Research (CPL), Leipzig University, University Hospital for Children and Adolescents Leipzig, LIFE Child, Leipzig, Germany.
Antje KörnerMedical Faculty, Center for Pediatric Research (CPL), Leipzig University, University Hospital for Children and Adolescents Leipzig, LIFE Child, Leipzig, Germany.
Ellen Schulz-KornasDepartment of Cariology, Endodontology and Periodontology, University of Leipzig, Leipzig, Germany.
Rainer HaakDepartment of Cariology, Endodontology and Periodontology, University of Leipzig, Leipzig, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo evaluate the diagnostic agreement between clinical examinations and time-delayed remote diagnostic assessments of intraoral 3D scans (IOS) for detecting oral diseases in children and adolescents, validating intraoral 3D scans as a tool in epidemiology studies. MATERIALS AND

methodsA total of 511 participants aged 7.5-20.5 years from the LIFE Child cohort received standardized chairside clinical diagnostics followed by intraoral 3D scanning (TRIOS 5, 3shape). Two calibrated examiners independently performed blinded remote review of digital scans after a predefined latency period. Diagnostic parameters comprised caries (ICDAS II), MIH classification, restorative status, sealant status, and plaque accumulation quantified using the Plaque Index (PI). Primary outcomes were diagnostic agreement and interrater reliability, analysed by weighted percent agreement, Cohen's weighted Kappa and Bland-Altman plots.

resultsVery high agreement was observed between clinical and IOS-based assessments for caries experience (DMF-T: [Formula: see text]= 0.990, κ = 0.77; dmf-t: [Formula: see text]= 0.991, κ = 0.93) and for severity-graded caries lesions (ICDAS 3-4: [Formula: see text]= 0.998, κ = 0.69; ICDAS 5-6: [Formula: see text]= 1.000, κ = 0.87). Agreement for initial lesions (ICDAS 1-2) was lower than for the more advanced lesions ([Formula: see text]= 0.979, κ = 0.29). Fissure sealants and fillings showed excellent agreement ([Formula: see text]= 0.997, κ = 0.84 and [Formula: see text]= 0.998, κ = 0.71). MIH detection on at least one tooth showed very good agreement ([Formula: see text] = 0.932, κ = 0.83), with consistently high agreement across severity codes. Plaque assessment showed good agreement overall ([Formula: see text] = 0.898), with slightly higher agreement in anterior regions. Interrater reliability was substantial to excellent across parameters.

conclusionsIntraoral 3D scans enable reliable remote assessment of clinically relevant dental conditions in children and adolescents, particularly for advanced caries lesions and molar incisor hypomineralisation (MIH). CLINICAL RELEVANCE: Intraoral 3D scanning enables efficient remote evaluation in screening and epidemiological programs, prioritizing visually distinct or treatment-relevant findings, with slightly reduced alignment for early enamel findings.

Indexed as

Dental CariesDental PlaqueImaging, Three-DimensionalAdolescentChildDental Plaque IndexFemaleHumansMaleMolar HypomineralizationReproducibility of ResultsAdolescentChildDental CariesDigital DentistryIntraoral ScannerMolar-Incisor Hypomineralisation

Identifiers

PMID42207321
PMCPMC13219214

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.