Evidence map›Paper›PMID 42207261›Full record

ArticlePediatric radiology2026

Super-resolution deep learning reconstruction achieves low-dose high-resolution imaging in pediatric cardiac computed tomography.

Haruka Obinata, Kiyohiro Takigiku, Kosuke Yonehara, Yuma Shibuya, Yohei Akazawa, Kohta Takei, Daisuke Miyazawa, Taro Sakashita

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Article in Pediatric radiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

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8 authors.

Haruka ObinataDepartment of Pediatric Cardiology, Nagano Children's Hospital, 3100 Toyoshina, Azumino, Nagano, 399-8288, Japan.
Kiyohiro TakigikuDepartment of Pediatric Cardiology, Nagano Children's Hospital, 3100 Toyoshina, Azumino, Nagano, 399-8288, Japan. tackymr2@me.com.
Kosuke YoneharaDepartment of Pediatric Cardiology, Nagano Children's Hospital, 3100 Toyoshina, Azumino, Nagano, 399-8288, Japan.
Yuma ShibuyaDepartment of Pediatric Cardiology, Nagano Children's Hospital, 3100 Toyoshina, Azumino, Nagano, 399-8288, Japan.
Yohei AkazawaDepartment of Pediatric Cardiology, Nagano Children's Hospital, 3100 Toyoshina, Azumino, Nagano, 399-8288, Japan.
Kohta TakeiDepartment of Pediatric Cardiology, Nagano Children's Hospital, 3100 Toyoshina, Azumino, Nagano, 399-8288, Japan.
Daisuke MiyazawaCanon Medical Systems Corporation, Otawara, Tochigi, Japan.
Taro SakashitaCanon Medical Systems Corporation, Otawara, Tochigi, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCardiac computed tomography (CT) is widely utilized in pediatric cardiology, but minimizing radiation exposure is essential. Recently, super-resolution deep learning reconstruction (SR-DLR) has emerged as a potential advancement over conventional deep learning reconstruction (C-DLR).

objectiveTo evaluate the potential of SR-DLR for further radiation dose reduction in pediatric cardiac CT through a comparison with C-DLR. MATERIALS AND

methodsThe phantom-based study assessed noise power spectrum and spatial resolution. For the clinical study, we compared nine C-DLR images (conventional radiation dose) and 11 SR-DLR images (lower radiation dose). Evaluation metrics included noise levels, contrast-to-noise ratio, and edge rise distance and edge rise slope.

resultsIn the phantom-based study, SR-DLR (250 mA) displayed equivalent noise characteristics as C-DLR (800 mA) while achieving superior spatial resolution. In clinical images, preliminary comparisons within the high-dose group revealed that SR-DLR significantly outperformed C-DLR in spatial resolution metrics, specifically edge rise distance and edge rise slope (P<0.001). Furthermore, despite the lower radiation dose used for SR-DLR than for C-DLR (volume CT dose index, 4.25±0.54 mGy vs. 13.3±6.43 mGy), there were no significant differences in noise, contrast resolution, and spatial resolution between the groups.

conclusionSR-DLR maintains non-inferior image quality compared with C-DLR even at reduced radiation doses. These findings substantiate the potential for further dose reduction in pediatric cardiac CT without compromising image quality.

Indexed as

Deep LearningHeart Defects, CongenitalRadiographic Image Interpretation, Computer-AssistedTomography, X-Ray ComputedChildChild, PreschoolFemaleHumansInfantMalePhantoms, ImagingRadiation DosageCardiologyComputed tomographyDeep learningImage reconstructionPediatricRadiation dose

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.