Evidence map›Paper›PMID 42207247›Full record

ArticleNeuroradiology2026

Diagnostic accuracy of [

Tahereh Ghaedian, Hamid Aghaei, Abbas Rakhsha, Mehrnaz Ghaedian, Abdolmajid Alipour, Shabnam Shariat, Zahra Shabani, Keyvan Eghbal, Mohammad Jamali, Abdolkarim Rahmanian and 3 more

Abstract read
PubMed Publisher
In one paragraph

Article in Neuroradiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Tahereh GhaedianNamazi Hospital, Shiraz University of Medical Sciences, Shiraz, Iran, Islamic Republic of.
Hamid AghaeiShiraz University of Medical Sciences, Shiraz, Iran, Islamic Republic of. hamidaghaei.khs@gmail.com.
Abbas RakhshaShiraz University of Medical Sciences, Shiraz, Iran, Islamic Republic of. abbasrakhsha4@gmail.com.
Mehrnaz GhaedianShiraz University of Medical Sciences, Shiraz, Iran, Islamic Republic of.
Abdolmajid AlipourNamazi Hospital, Shiraz University of Medical Sciences, Shiraz, Iran, Islamic Republic of.
Shabnam ShariatNamazi Hospital, Shiraz University of Medical Sciences, Shiraz, Iran, Islamic Republic of.
Zahra ShabaniNamazi Hospital, Shiraz University of Medical Sciences, Shiraz, Iran, Islamic Republic of.
Keyvan EghbalShiraz University of Medical Sciences, Shiraz, Iran, Islamic Republic of.
Mohammad JamaliShiraz University of Medical Sciences, Shiraz, Iran, Islamic Republic of.
Abdolkarim RahmanianShiraz University of Medical Sciences, Shiraz, Iran, Islamic Republic of.
Ehsan MohammadhosseiniShiraz University of Medical Sciences, Shiraz, Iran, Islamic Republic of.
Zahra AshrafiTabriz University of Medical Sciences, Tabriz, Iran, Islamic Republic of.
Manouchehr DavlatovShiraz University of Medical Sciences, Shiraz, Iran, Islamic Republic of.

Funding

Shiraz University of Medical Sciences 25169
6 · The paper itself

Abstract

objectiveThis study aimed to evaluate the diagnostic accuracy of [

methodsIn this cross-sectional study, 31 lesions with suspected glioblastoma recurrence underwent [

resultsAmong the 30 patients with 31 lesions (70% male, mean age 46 years), initial MRI identified recurrence in 38.71% (n = 12), no recurrence in 35.48% (n = 11), and was indeterminate in 25.81% (n = 8) of lesions. Follow-up MRI and other clinical data confirmed recurrence in 58.06% (n = 18) and no recurrence in 41.94% (n = 13). Quantitative SPECT/CT analysis revealed a mean TBR of 13.08 ± 12.09. Visual PSMA assessment demonstrated a sensitivity of 83% and specificity of 92% when considering moderate/high uptake as positive. TBR quantitative analysis showed excellent discrimination (AUC = 0.87), with an optimal threshold of 7.55 yielding 89% sensitivity and 91% specificity. Initial MRI had 100% sensitivity and 91.67% specificity when excluding indeterminate cases. For the 8 patients with indeterminate initial MRI, both visual and quantitative PSMA parameters showed 100% accuracy in predicting the final diagnosis.

conclusion[

Indexed as

Brain NeoplasmsGlioblastomaNeoplasm Recurrence, LocalOrganotechnetium CompoundsSingle Photon Emission Computed Tomography Computed TomographyAdultAgedCross-Sectional StudiesDiagnosis, DifferentialFemaleGallium RadioisotopesHumansHydrazinesMagnetic Resonance ImagingMaleMiddle AgedGallium RadioisotopesHydrazinesOctreotideOrganotechnetium CompoundsPSMA-11Radiopharmaceuticalstechnetium Tc 99m hydrazinonicotinyl-Tyr(3)-octreotideDiagnostic accuracyGlioblastomaMRIPSMA SPECT/CTRecurrence

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.