Evidence map›Paper›PMID 42207201›Full record

ArticleClinical oral investigations2026

Oral health and its association with dysphagia severity and nutritional vulnerability after stroke: a structural equation modeling study.

Mohit Kothari, Silas Alves-Costa, Susilena Arouche Costa, Abhishek Kumar, Gustavo G Nascimento, Jørgen Feldbaek Nielsen, Peter Svensson, Simple F Kothari

Abstract read
In one paragraph

Article in Clinical oral investigations, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Mohit KothariHammel Neurorehabilitation Centre and University Research Clinic, Department of Clinical Medicine, Aarhus University, Hammel, Denmark. kothari@health.sdu.dk.
Silas Alves-CostaDentistry Graduate Program, Federal University of Maranhão, São Luís, MA, Brazil.
Susilena Arouche CostaDentistry Graduate Program, CEUMA University, São Luís, MA, Brazil.
Abhishek KumarDivision of Oral Diagnostics and Rehabilitation, Department of Dental Medicine, Karolinska Institute, Huddinge, Sweden.
Gustavo G NascimentoSchool of Dentistry, University of Utah, Salt Lake City, UT, USA.
Jørgen Feldbaek NielsenHammel Neurorehabilitation Centre and University Research Clinic, Department of Clinical Medicine, Aarhus University, Hammel, Denmark.
Peter SvenssonFaculty of Dentistry, National University of Singapore, Queenstown, Singapore.
Simple F KothariHammel Neurorehabilitation Centre and University Research Clinic, Department of Clinical Medicine, Aarhus University, Hammel, Denmark.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundOral health deterioration is common after neurological injury and may contribute to functional impairment beyond the oral cavity. In stroke rehabilitation, impaired oral conditions coexist with orofacial dysfunction and dysphagia, yet the mechanistic pathways linking oral health to swallowing impairment and downstream nutritional consequences remain poorly defined. This study examined the interrelationships between oral health, orofacial function, dysphagia, and malnutrition using structural equation modelling (SEM).

methodsNinety-two stroke survivors admitted to a neurorehabilitation center underwent standardized assessments of oral health, orofacial function, dysphagia severity at admission, and nutritional screening at week 4. Oral health and orofacial function were modelled as latent variables. SEM was used to quantify pathways linking oral health to malnutrition risk, with bivariate comparisons stratified by dysphagia status.

resultsPoor oral health was significantly associated with reduced orofacial function (β = -0.41, p < 0.001), which in turn was associated with dysphagia severity (β = -0.51, p < 0.001). Dysphagia showed a direct association with malnutrition risk (β = 0.31, p = 0.031). While poor oral health exerted a direct effect on malnutrition risk (β = 0.33, p = 0.023), the indirect pathway linking poor oral health to malnutrition through orofacial dysfunction and dysphagia was not statistically significant (β = 0.063, p = 0.091). The model identified a coherent oral-orofacial-swallowing pathway consistent with nutritional vulnerability after stroke.

conclusionThese findings position oral health as an important factor associated with swallowing impairment and nutritional vulnerability after stroke within a modeled pathway. Integrating oral and orofacial assessments into post-stroke care may support earlier identification of patients at risk for functional decline and systemic complications. CLINICAL SIGNIFICANCE: Oral health deterioration was associated with malnutrition risk after stroke, directly and via impaired orofacial function and dysphagia. Integrating oral and orofacial function measures into routine post-stroke assessments may improve early risk stratification and support coordinated dental and rehabilitation care.

Indexed as

Deglutition DisordersMalnutritionOral HealthStrokeAgedFemaleHumansLatent Class AnalysisMaleMiddle AgedNutritional StatusRisk FactorsSeverity of Illness IndexDysphagiaMalnutritionNutritional RiskOral HealthOrofacial FunctionStroke.Structural Equation Modelling

Identifiers

PMID42207201
PMCPMC13219075

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.