ArticleJACC. Advances2026
Venous Excess Ultrasound Score and Acute Kidney Injury in Patients With Acute Heart Failure.
Article in JACC. Advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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Who cites it
1 citing paper in PubMed.
- Systemic Venous Excess in Acute Heart Failure: A Retrograde Signal of Right Ventricular Uncoupling.JACC. Advances · 2026Article
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20 authors.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundSystemic venous congestion is associated with an increased risk of acute kidney injury (AKI) in critically ill patients. Venous Excess Ultrasound Score (VExUS) has been proposed as a noninvasive tool for assessing venous congestion based on ultrasonographic evaluation of the inferior vena cava, hepatic vein flow, portal vein pulsatility, and intrarenal Doppler flow.
objectivesThe authors aimed to evaluate the association between the VExUS score and AKI in patients with acute heart failure (AHF).
methodsProspective study including patients with AHF (acute de novo and decompensated chronic heart failure). VExUS was performed within the first 8 hours of hospital stay. Patients were classified by presence of severe congestion (VExUS 0-1/2-3). The primary objective was AKI, defined by Kidney Disease: Improving Global Outcomes criteria. Secondary objectives included the composite of AKI, cardiogenic shock, and all-cause mortality.
resultsA total of 109 patients were included. After ultrasound assessment, 41 (37.2%) were categorized as having significant congestion (VExUS >1). VExUS >1 was more frequent in chronic HF and in patients with right ventricular involvement. At each increasing VExUS grade, a higher proportion developed AKI: VExUS = 0 (29.2%), VExUS = 1 (44%), VExUS = 2 (66.6%), and VExUS = 3 (60.7%) (P = 0.008). A significantly increased risk of AKI (HR: 2.65; 95% CI: 1.39-5.07; P = 0.003) was found in patients with VExUS >1. Adjusted logistic regression showed VExUS >1 as the strongest predictor (OR: 4.60; 95% CI: 1.47-16.0) of AKI during hospital stay.
conclusionsIn AHF patients, the VExUS score is associated with AKI occurrence. Further studies are needed to clarify the role of VExUS assessment in HF.
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