Evidence map›Paper›PMID 42206684›Full record

ArticleMovement disorders clinical practice2026

ON/OFF Phenomenon in 4-Aminopyridine Therapy in Spinocerebellar Ataxia 27B: Therapeutic and Diagnostic Insights.

Chiara Caneda, Eleonora Bertoncello, Alessia Peghin, Sara Satolli, Filippo Maria Santorelli, Michele Tinazzi, Ilaria Antonella Di Vico

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Movement disorders clinical practice, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Chiara Caneda *Neurology Unit, Department of Neurosciences, Biomedicine and Movement Sciences, Policlinico Borgo Roma, University of Verona, Verona, Italy.
Eleonora Bertoncello *Neurology Unit, Department of Neurosciences, Biomedicine and Movement Sciences, Policlinico Borgo Roma, University of Verona, Verona, Italy.
Alessia PeghinNeurology Unit, Department of Neurosciences, Biomedicine and Movement Sciences, Policlinico Borgo Roma, University of Verona, Verona, Italy.
Sara SatolliDivision of Neurology and Neurorehabilitation, Department of Neurosciences and Rehabilitation, Santobono Pausilipon Children's Hospital (AORN Santobono Pausilipon), Naples, Italy.
Filippo Maria Santorelli *Molecular Medicine for Neurodegenerative and Neuromuscular Diseases Unit, IRCCS Stella Maris Foundation, Pisa, Italy.
Michele Tinazzi *Neurology Unit, Department of Neurosciences, Biomedicine and Movement Sciences, Policlinico Borgo Roma, University of Verona, Verona, Italy.ORCID https://orcid.org/0000-0002-2370-7063
Ilaria Antonella Di Vico *Neurology Unit, Department of Neurosciences, Biomedicine and Movement Sciences, Policlinico Borgo Roma, University of Verona, Verona, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

4‐aminopyridineSCA27Bspinocerebellar ataxia 27B

Identifiers

PMID42206684
PMCPMC13339576

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.