Evidence map›Paper›PMID 42206584›Full record

ArticleMuscle & nerve2026

Ultrasound-Confirmed Median Nerve Pseudoconduction Block due to Anatomical Variation.

Yajing Ye, Bashar Katirji, Robert D Adams

Abstract read
In one paragraph

Article in Muscle & nerve, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Yajing YeNeuromuscular Center & EMG Laboratory, the Neurological Institute, University Hospitals Cleveland Medical Center, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA.ORCID https://orcid.org/0009-0003-3511-8674
Bashar KatirjiNeuromuscular Center & EMG Laboratory, the Neurological Institute, University Hospitals Cleveland Medical Center, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA.ORCID https://orcid.org/0000-0001-7634-975X
Robert D AdamsNeuromuscular Center & EMG Laboratory, the Neurological Institute, University Hospitals Cleveland Medical Center, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA.ORCID https://orcid.org/0009-0005-2499-6134

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

INTRODUCTION/

aimsConduction block (CB) at non-entrapment sites is an important electrodiagnostic (EDX) feature supporting acquired demyelinating neuropathies. However, anatomical variation may produce pseudoconduction block, mimicking true CB. After encountering a patient with median nerve pseudoconduction block due to anatomical variation, we aimed to assess the frequency of this variation, its impact on EDX interpretation, and the role of neuromuscular ultrasound (NMUS) in improving diagnostic accuracy.

methodsWe describe an index patient with median nerve pseudoconduction block in the forearm caused by anatomical variation, confirmed by ultrasound. We then retrospectively reviewed upper limb NMUS performed by a single EDX medicine specialist at University Hospitals Cleveland Medical Center. At the antecubital fossa, the distance between the midpoint of the brachial artery and the midpoint of the median nerve was measured. Available EDX values were reviewed for ultrasounds with marked nerve-artery separation.

resultsSixty-eight patients were included. In all patients, the median nerve lay medial to the brachial artery (range: 2.5-26 mm). Seven patients (10.3%) had nerve-artery separation greater than 12.5 mm. Of these, five had available EDX data for retrospective review and three (60%) reported either complete or partial CB. DISCUSSION: True CB suggests significant pathology. NMUS can help distinguish pseudoconduction block from true CB and prevent misdiagnosis. When pseudoconduction block of the median nerve in the forearm is suspected, stimulation 15-25 mm medial to the brachial artery pulse, or slightly more medial and proximal (between the bicep tendon and brachialis muscle) may improve accuracy.

Indexed as

Median NerveAdultAgedAged, 80 and overFemaleHumansMaleMiddle AgedNerve Conduction StudiesNeural ConductionRetrospective StudiesUltrasonographyanatomical variantEDXmedian nerve pseudoconduction blockneuromuscular ultrasoundultrasound guided electrodiagnostic testing

Identifiers

PMID42206584
PMCPMC13332558

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.