Evidence map›Paper›PMID 42206371›Full record

ArticleArteriosclerosis, thrombosis, and vascular biology2026

Angiotensin II Induces Abdominal Aortic Branch Aneurysms in

Michael K Franklin, Deborah A Howatt, Jessica J Moorleghen, Mary B Sheppard, Yuriko Katsumata, Hisashi Sawada, Hong S Lu, Alan Daugherty

Abstract read
In one paragraph

Article in Arteriosclerosis, thrombosis, and vascular biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Michael K FranklinSaha Cardiovascular Research Center (M.K.F., D.A.H., J.J.M., M.B.S., H.S., H.S.L., A.D.), University of Kentucky, Lexington.ORCID 0000-0003-4993-0164
Deborah A HowattSaha Cardiovascular Research Center (M.K.F., D.A.H., J.J.M., M.B.S., H.S., H.S.L., A.D.), University of Kentucky, Lexington.ORCID 0000-0002-0078-092X
Jessica J MoorleghenSaha Cardiovascular Research Center (M.K.F., D.A.H., J.J.M., M.B.S., H.S., H.S.L., A.D.), University of Kentucky, Lexington.ORCID 0000-0002-2556-6719
Mary B SheppardSaha Cardiovascular Research Center (M.K.F., D.A.H., J.J.M., M.B.S., H.S., H.S.L., A.D.), University of Kentucky, Lexington.ORCID 0000-0003-0026-8640
Yuriko KatsumataDivision of Biomedical Informatics (Y.K.), University of Kentucky, Lexington.ORCID 0000-0002-0188-8094
Hisashi SawadaSaha Cardiovascular Research Center (M.K.F., D.A.H., J.J.M., M.B.S., H.S., H.S.L., A.D.), University of Kentucky, Lexington.ORCID 0000-0003-0017-6236
Hong S LuSaha Cardiovascular Research Center (M.K.F., D.A.H., J.J.M., M.B.S., H.S., H.S.L., A.D.), University of Kentucky, Lexington.ORCID 0000-0002-0577-2558
Alan DaughertySaha Cardiovascular Research Center (M.K.F., D.A.H., J.J.M., M.B.S., H.S., H.S.L., A.D.), University of Kentucky, Lexington.ORCID 0000-0003-2093-3775

Funding

Determinants of Aorta HeterogeneityR35HL155649 · NHLBI · UNIVERSITY OF KENTUCKY · PI Alan Daugherty · 2021 to 2026
$5.3M
Pharmacological Mechanistic Insights into Thoracic Aortic AneurysmK01HL149984 · NHLBI · UNIVERSITY OF KENTUCKY · PI SHEPPARD, MARY BURCHETT · 2021 to 2025
$886k
NHLBI NIH HHS K01 HL149984NHLBI NIH HHS R35 HL155649
6 · The paper itself

Abstract

backgroundMice harboring a missense variant (C1041G) of

methods

resultsAngII infusion dramatically augmented aortopathy in

conclusionsAngII exacerbated aortic pathology in

Indexed as

Angiotensin IIAortic Aneurysm, AbdominalAortic DissectionFibrillin-1Mutation, MissenseAdipokinesAneurysm, Ascending AortaAnimalsAorta, ThoracicAortic RuptureBlood PressureDisease Models, AnimalFemaleGenetic Predisposition to DiseaseMaleMiceAdipokinesAngiotensin IIFbn1 protein, mouseFibrillin-1Norepinephrineangiotensin IIfibrillin-1micenorepinephrinetomography

Identifiers

PMID42206371
PMCPMC13220914

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.