Evidence map›Paper›PMID 42206058›Full record

ArticleFrontiers in immunology2026

Temporal transcriptional dynamics in cutaneous leishmaniasis reveal novel targets for therapeutic interventions in a dermal mouse model.

Jessica Lobo-Silva, Cibele Orge, Almiro Pires da Silva Neto, Bruno Vinagre Ribeiro, Regiane Degan Fávaro, Joyce Karoline da Silva, Sara Patrícia de Oliveira Santos, Sara Nunes, Valdomiro Silveira Moitinho-Junior, Aldina Barral and 4 more

Abstract read
In one paragraph

Article in Frontiers in immunology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Jessica Lobo-SilvaLaboratório de Medicina e Saúde Pública de Precisão (MeSP2), Instituto Gonçalo Moniz, Fundação Oswaldo Cruz, Salvador, Brazil.
Cibele OrgeLaboratório de Medicina e Saúde Pública de Precisão (MeSP2), Instituto Gonçalo Moniz, Fundação Oswaldo Cruz, Salvador, Brazil.
Almiro Pires da Silva NetoLaboratório de Medicina e Saúde Pública de Precisão (MeSP2), Instituto Gonçalo Moniz, Fundação Oswaldo Cruz, Salvador, Brazil.
Bruno Vinagre RibeiroLaboratório de Medicina e Saúde Pública de Precisão (MeSP2), Instituto Gonçalo Moniz, Fundação Oswaldo Cruz, Salvador, Brazil.
Regiane Degan FávaroDepartamento de Ciências da Vida, Universidade do Estado da Bahia, Salvador, Brazil.
Joyce Karoline da SilvaLaboratório de Medicina e Saúde Pública de Precisão (MeSP2), Instituto Gonçalo Moniz, Fundação Oswaldo Cruz, Salvador, Brazil.
Sara Patrícia de Oliveira SantosLaboratório de Medicina e Saúde Pública de Precisão (MeSP2), Instituto Gonçalo Moniz, Fundação Oswaldo Cruz, Salvador, Brazil.
Sara NunesLaboratório de Medicina e Saúde Pública de Precisão (MeSP2), Instituto Gonçalo Moniz, Fundação Oswaldo Cruz, Salvador, Brazil.
Valdomiro Silveira Moitinho-JuniorBiotério, Instituto Gonçalo Moniz, Fundação Oswaldo Cruz, Salvador, Brazil.
Aldina BarralLaboratório de Medicina e Saúde Pública de Precisão (MeSP2), Instituto Gonçalo Moniz, Fundação Oswaldo Cruz, Salvador, Brazil.
Natalia Tavares MachadoLaboratório de Medicina e Saúde Pública de Precisão (MeSP2), Instituto Gonçalo Moniz, Fundação Oswaldo Cruz, Salvador, Brazil.
Pablo Ivan Pereira RamosCentro de Integração de Dados e Conhecimento para Saúde, Instituto Gonçalo Moniz, Fundação Oswaldo Cruz, Salvador, Brazil.
Ricardo KhouriLaboratório de Medicina e Saúde Pública de Precisão (MeSP2), Instituto Gonçalo Moniz, Fundação Oswaldo Cruz, Salvador, Brazil.
Leonardo Paiva FariasLaboratório de Medicina e Saúde Pública de Precisão (MeSP2), Instituto Gonçalo Moniz, Fundação Oswaldo Cruz, Salvador, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cutaneous leishmaniasis (CL) caused by

Indexed as

Leishmania braziliensisLeishmaniasis, CutaneousTranscriptomeAnimalsDisease Models, AnimalFemaleGene Expression ProfilingGene Expression RegulationGene Regulatory NetworksHumansMiceMice, Inbred BALB CMicroRNAsSkinMicroRNAsBALB/c mouse modelcutaneous leishmaniasisimmune responseLeishmania braziliensismicroRNAs (miRNAs)transcriptomicswound healing

Identifiers

PMID42206058
PMCPMC13201149

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.