ArticleFrontiers in immunology2026
Time-resolved transcriptomics of haemocyte discrimination between challenges by nematodes and inert material in the oriental armyworm
Article in Frontiers in immunology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Corrections and comments
- Erratum issued
Authors and funding
8 authors.
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Abstract
Introduction: Insects defend against large metazoan parasites such as nematodes through haemocyte-mediated encapsulation, but how haemocytes respond to living parasites remains poorly understood. This study examined the cellular and transcriptional responses of haemocytes to living nematodes in the lepidopteran insect Methods: Encapsulation assays were combined with time-course transcriptomic analyses to compare haemocyte responses to inert polystyrene beads and the free-living nematode Results: Inert polystyrene beads were rapidly encapsulated, whereas Discussion: These findings show that haemocytes distinguish living nematodes from inert particles not merely through their physical presence, but by mounting sustained and coordinated transcriptional responses. This study provides a temporal and mechanistic framework for understanding how insect immune systems recognise and respond to large metazoan parasites.
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