Evidence map›Paper›PMID 42205821›Full record

ArticleFrontiers in medicine2026

A new direction in personalized medicine: multimodal joint prediction of hepatic encephalopathy risk post-TIPS.

Lin-Feng Zhou, Hao-Huan Tang, Jian Shen, Shuai Zhang, Wan-Ci Li, Jun Tao, Xiao-Li Zhu

Abstract read
In one paragraph

Article in Frontiers in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Lin-Feng Zhou *Department of Interventional Radiology, The First Affiliated Hospital of Soochow University, Suzhou, China.
Hao-Huan Tang *Department of Interventional Radiology, The First Affiliated Hospital of Soochow University, Suzhou, China.
Jian ShenDepartment of Interventional Radiology, The First Affiliated Hospital of Soochow University, Suzhou, China.
Shuai ZhangDepartment of Interventional Radiology, The First Affiliated Hospital of Soochow University, Suzhou, China.
Wan-Ci LiDepartment of Interventional Radiology, The First Affiliated Hospital of Soochow University, Suzhou, China.
Jun TaoDepartment of Radiology, Hubei Cancer Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Xiao-Li ZhuDepartment of Interventional Radiology, The First Affiliated Hospital of Soochow University, Suzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Overt hepatic encephalopathy (OHE) is a common complication after transjugular intrahepatic portosystemic shunt (TIPS), adversely affecting quality of life. This study aimed to develop a predictive model integrating manual imaging, radiomics, and clinical data to forecast OHE within 1 year post-TIPS. Methods: This retrospective study included 338 patients who underwent TIPS between November 2015 and January 2022, divided into training and validation sets (7:3). Feature selection was performed using Chi-square test, Results: Within 1 year after TIPS, 79 (33.4%) participants in the training group and 34 (33.3%) participants in validation group developed OHE. Three independent models and one combined model were established and evaluated in terms of their performance. The areas under the ROC curve of Model M, Model R, Model C, and Model MRC were 0.858 (95% CI: 0.809-0.907), 0.744 (95% CI: 0.681-0.808), 0.757 (95% CI: 0.692-0.821), and 0.902 (95% CI: 0.863-0.941), respectively. F1 scores were 0.861, 0.765, 0.797, and 0.891, respectively. Model MRC demonstrated superior performance compared to the other three models. Conclusion: Model MRC exhibited a considerable predictive ability for OHE within the first year after TIPS.

Indexed as

cirrhosishepatic encephalopathymachine learningradiomicstransjugular intrahepatic portosystemic shunt

Identifiers

PMID42205821
PMCPMC13201119

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.