Evidence map›Paper›PMID 42205779›Full record

ArticleFrontiers in human neuroscience2026

State-dependent modulation of brain co-activation patterns induced by individually targeted VLPFC stimulation during viewing emotional film clips.

Changyue Hou, Meihua Yan, Haonan Pei, Ting Ye, Sisi Jiang, Hechun Li, Roberto Rodríguez-Labrada, Dezhong Yao, Cheng Luo

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In one paragraph

Article in Frontiers in human neuroscience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Changyue HouThe Clinical Hospital of Chengdu Brain Science Institute, MOE Key Lab for Neuroinformation, School of Life Science and Technology, University of Electronic Science and Technology of China, Chengdu, China.
Meihua YanThe Clinical Hospital of Chengdu Brain Science Institute, MOE Key Lab for Neuroinformation, School of Life Science and Technology, University of Electronic Science and Technology of China, Chengdu, China.
Haonan PeiThe Clinical Hospital of Chengdu Brain Science Institute, MOE Key Lab for Neuroinformation, School of Life Science and Technology, University of Electronic Science and Technology of China, Chengdu, China.
Ting YeThe Clinical Hospital of Chengdu Brain Science Institute, MOE Key Lab for Neuroinformation, School of Life Science and Technology, University of Electronic Science and Technology of China, Chengdu, China.
Sisi JiangThe Clinical Hospital of Chengdu Brain Science Institute, MOE Key Lab for Neuroinformation, School of Life Science and Technology, University of Electronic Science and Technology of China, Chengdu, China.
Hechun LiThe Clinical Hospital of Chengdu Brain Science Institute, MOE Key Lab for Neuroinformation, School of Life Science and Technology, University of Electronic Science and Technology of China, Chengdu, China.
Roberto Rodríguez-LabradaCuban Neuroscience Center, La Habana, Cuba.
Dezhong YaoThe Clinical Hospital of Chengdu Brain Science Institute, MOE Key Lab for Neuroinformation, School of Life Science and Technology, University of Electronic Science and Technology of China, Chengdu, China.
Cheng LuoThe Clinical Hospital of Chengdu Brain Science Institute, MOE Key Lab for Neuroinformation, School of Life Science and Technology, University of Electronic Science and Technology of China, Chengdu, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Accumulating evidence indicates that repetitive transcranial magnetic stimulation (rTMS) outcomes are state-dependent, with ongoing emotional states influencing neuromodulatory effects. However, how emotional context during stimulation influences subsequent brain functional state organization remains unclear. A total of 99 healthy participants were recruited in this study and allocated to one of three groups: active rTMS with sad film viewing (sad group), active rTMS with neutral film viewing (neutral group), or sham rTMS with sad film viewing (sham group). We combined rTMS during emotional film viewing with co-activation pattern (CAP) analysis to investigate the potential state-dependent effects of rTMS on brain dynamics. The fraction of time, resilience, and transition probabilities of CAPs were calculated to characterize brain dynamics. Four recurring CAPs were identified in this study. Relative to the sham group, participants following stimulation during the sad condition exhibited increased engagement of CAP 2, characterized by deactivations in the frontoparietal network and co-activations of the visual and somatomotor networks, along with decreased engagement of CAP 4, characterized by deactivations in the default mode network and co-activations of the somatomotor and salience networks. In contrast, the neutral condition exhibited attenuated effects. Furthermore, the change in transition probability from CAP 2 to CAP 3 was significantly greater in the sad condition than in the neutral condition. Together, these findings indicate that the effects of rTMS on brain dynamics may be modulated by the emotional context during stimulation. This work offers novel insights into the state-dependent modulation by rTMS and may help inform the optimization of therapeutic outcomes for rTMS interventions.

Indexed as

brain dynamicsco-activation patternemotional inductionrTMSstate-dependent

Identifiers

PMID42205779
PMCPMC13201408

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.