ArticleFrontiers in pediatrics2026
Retrospective comparison of two distinct dual-induction strategies in pediatric kidney transplantation: three doses vs. a single dose of rabbit antithymocyte globulin, each combined with two basiliximab doses.
Article in Frontiers in pediatrics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: We retrospectively compared two distinct dual-induction strategies in pediatric kidney transplantation. Methods: Patients transplanted at our center prior to 15 February 2020 were scheduled to receive three doses of rabbit antithymocyte globulin (rATG; 1.0 mg/kg/dose) along with two doses of basiliximab ( Results: Median follow-up in both groups was 24 mo post-transplant. In the single-dose ITT rATG group, a higher proportion of patients developed a first BPAR [ Conclusions: A lower rate of first BPAR but a somewhat higher rate of viral infection was observed in the three-dose ITT rATG group. These study results support the use of tailored induction protocols to optimize effective immunosuppression while minimizing adverse effects in pediatric kidney transplantation.
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