ArticleFrontiers in pediatrics2026
Evaluation of antibiotic consumption and resistance patterns among neonates: a 10-year retrospective study.
Article in Frontiers in pediatrics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Newborns are highly susceptible to infection, which leads to a higher chance of antibiotic utilization and resistance. Thus, the current study was carried out to evaluate antibiotic consumption, susceptibility, and resistance patterns among neonates. Methods: A retrospective study was conducted in a tertiary care hospital over 10 years to evaluate antibiotic consumption and resistance patterns among neonates. Antibiotic utilization was calculated using the defined daily dose (DDD) and days of therapy (DOT) based approach. All the data were analysed using SPSS version 29. Results: A total of 447 neonates were included in the study. Aminoglycosides (DDD:3089.449, DOT:2915), penicillin (DDD:3003.22, DOT:2218), and cephalosporins (DDD:1164.88, DOT:744) were the top three commonly prescribed classes of antibiotics. A total of 21 microorganisms were identified among neonates, of which Conclusion: Aminoglycosides and penicillin are the most commonly prescribed antibiotics with higher resistance among neonates, pointing towards the need for the implementation of an antimicrobial stewardship program in neonatal settings.
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