Evidence map›Paper›PMID 42205705›Full record

ArticleiScience2026

Initial biomarker testing strategies and clinical outcomes in advanced non-small cell lung cancer.

Masaki Ishida, Tadaaki Yamada, Yasuhiro Goto, Taiichiro Otsuki, Hirokazu Taniguchi, Taishi Harada, Akihiro Yoshimura, Shinsuke Shiotsu, Asuka Okada, Kazuki Jinno and 11 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in iScience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

Masaki IshidaDepartment of Pulmonary Medicine, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kajii-cho, Kamigyo-ku, Kyoto, Japan.
Tadaaki YamadaDepartment of Pulmonary Medicine, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kajii-cho, Kamigyo-ku, Kyoto, Japan.
Yasuhiro GotoDepartment of Respiratory Medicine, Fujita Health University School of Medicine, Toyoake, Aichi, Japan.
Taiichiro OtsukiDepartment of Respiratory Medicine and Hematology, School of Medicine, Hyogo Medical University, Nishinomiya, Hyogo, Japan.
Hirokazu TaniguchiDepartment of Respiratory Medicine, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan.
Taishi HaradaDepartment of Medical Oncology, Fukuchiyama City Hospital, Fukuchiyama, Kyoto, Japan.
Akihiro YoshimuraDepartment of Respiratory Medicine, Japanese Red Cross Kyoto Daini Hospital, Kyoto, Japan.
Shinsuke ShiotsuDepartment of Respiratory Medicine, Japanese Red Cross Kyoto Daini Hospital, Kyoto, Japan.
Asuka OkadaDepartment of Respiratory Medicine, Saiseikai Suita Hospital, Suita, Osaka, Japan.
Kazuki JinnoDepartment of Respiratory Medicine, Japanese Red Cross Kyoto Daiichi Hospital, Kyoto, Japan.
Hibiki KandaDepartment of Respiratory Medicine, Omi Medical Center, Kusatsu, Shiga, Japan.
Noeru InoguchiDepartment of Pulmonary Medicine, Otsu City Hospital, Otsu, Shiga, Japan.
Mototaka FukuiDepartment of Respiratory Medicine, Uji-Tokushukai Medical Center, Kyoto, Japan.
Takahiro YamadaDepartment of Pulmonary Medicine, Matsushita Memorial Hospital, Osaka, Japan.
Tae HataDepartment of Pulmonary Medicine, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kajii-cho, Kamigyo-ku, Kyoto, Japan.
Hayato KawachiDepartment of Pulmonary Medicine, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kajii-cho, Kamigyo-ku, Kyoto, Japan.
Yuki KatayamaDepartment of Pulmonary Medicine, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kajii-cho, Kamigyo-ku, Kyoto, Japan.
Kenji MorimotoDepartment of Pulmonary Medicine, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kajii-cho, Kamigyo-ku, Kyoto, Japan.
Masahiro IwasakuDepartment of Pulmonary Medicine, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kajii-cho, Kamigyo-ku, Kyoto, Japan.
Takashi KijimaDepartment of Respiratory Medicine and Hematology, School of Medicine, Hyogo Medical University, Nishinomiya, Hyogo, Japan.
Koichi TakayamaDepartment of Pulmonary Medicine, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kajii-cho, Kamigyo-ku, Kyoto, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Appropriate initial biomarker testing is essential for treatment selection in patients with advanced non-small cell lung cancer (NSCLC). We conducted a multicenter retrospective study comparing single-plex and multiplex testing strategies for driver oncogene detection and clinical outcomes. Single-plex testing was associated with a higher detection rate of epidermal growth factor receptor (

Indexed as

Health sciences

Identifiers

PMID42205705
PMCPMC13206649

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.