Evidence map›Paper›PMID 42205703›Full record

ArticleiScience2026

Universal principles of cell population growth follow from local contact inhibition.

Gregory J Kimmel, Sadegh Marzban, Mehdi Damaghi, Arne Traulsen, Alexander R A Anderson, Jeffrey West, Philipp M Altrock

Abstract read
In one paragraph

Article in iScience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Spatial interactions modulate tumor growth and immune infiltration.bioRxiv : the preprint server for biology · 2024
    Article
  4. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Gregory J KimmelDepartment of Integrated Mathematical Oncology, Moffitt Cancer Center, Tampa, FL 33612, USA.
Sadegh MarzbanDepartment of Integrated Mathematical Oncology, Moffitt Cancer Center, Tampa, FL 33612, USA.
Mehdi DamaghiStony Brook Cancer Center, Stony Brook School of Medicine, Stony Brook University, Stony Brook, NY 11794, USA.
Arne TraulsenDepartment of Theoretical Biology, Max Planck Institute for Evolutionary Biology, Plön 24306, Germany.
Alexander R A AndersonDepartment of Integrated Mathematical Oncology, Moffitt Cancer Center, Tampa, FL 33612, USA.
Jeffrey WestDepartment of Integrated Mathematical Oncology, Moffitt Cancer Center, Tampa, FL 33612, USA.
Philipp M AltrockDepartment of Theoretical Biology, Max Planck Institute for Evolutionary Biology, Plön 24306, Germany.

Funding

The Delta Ecology of NSCLC TreatmentU54CA274507 · NCI · H. LEE MOFFITT CANCER CTR & RES INST · PI Alexander Robertson Allan Anderson, ROBERT A GATENBY · 2023 to 2026
$9.4M
NCI NIH HHS U54 CA274507
6 · The paper itself

Abstract

Cancer cell populations often exhibit remarkably similar growth laws despite their heterogeneity. Explanations of universal cell population growth remain partly unresolved to this day. Here, we present a growth-law unification by investigating the connection between the microscopic assumptions that affect the expected contact inhibition leading to five classical tumor growth laws: exponential, radial growth, fractal growth, generalized logistic, and Gompertzian growth. All five can be seen as manifestations of a single microscopic model. Agent-based simulations substantiate our theory, and we can explain differences in growth curves in experimental data from

Indexed as

Systems biology

Identifiers

PMID42205703
PMCPMC13207371

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.