ArticleiScience2026
Twitching in sleeping premature infants provides a sensitive behavioral assay of early motor control.
Article in iScience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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1 citing paper in PubMed.
- REM-sleep twitching in adults and the maintenance of specialized sensorimotor systems.Current biology : CB · 2026Review
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13 authors.
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Abstract
Limb twitching is among the earliest observable behaviors in human development and a hallmark of active (rapid eye movement, REM) sleep. Systematic assessments in full-term infants reveal a spatiotemporal organization of twitching that informal observation cannot. Because preterm infants spend even more time asleep and are at heightened risk for neurodevelopmental disorders, we provide the first systematic characterization of twitching at 34-35 weeks postmenstrual age. Preterm infants exhibit an immense quantity of twitching across the body, underscoring its potential functional significance. The spatiotemporal structure of twitching also changes with age, including a selective increase in finger and toe twitching. Unexpectedly, during periods of tracé alternant, a precursor to quiet sleep, twitching appears in brief bouts that are almost exclusively restricted to the legs. These findings show how this abundant but overlooked sleep behavior provides a sensitive assay of the developing neural control of movement, with implications for understanding typical and atypical development.
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