ArticleTransboundary and emerging diseases2026
Dynamic Antibody Responses in Porcine Epidemic Diarrhea Virus-Infected Pigs and Correlation of Prepartum Serum, Oral Swabs, and Rectal Swabs With Postpartum Colostral IgA and IgG in Sows.
Article in Transboundary and emerging diseases, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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Who cites it
1 citing paper in PubMed.
- Dynamic Antibody Responses in Porcine Epidemic Diarrhea Virus-Infected Pigs and Correlation of Prepartum Serum, Oral Swabs, and Rectal Swabs With Postpartum Colostral IgA and IgG in Sows.Transboundary and emerging diseases · 2026Article
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12 authors.
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Abstract
Porcine epidemic diarrhea (PED) is a highly contagious gastrointestinal disease caused by PED virus (PEDV), resulting in high mortality among neonatal piglets. Ensuring robust maternal immunity to provide protective colostral antibodies is critical for effective disease control. In this study, an enzyme-linked immunosorbent assay (ELISA) was employed to monitor antibody dynamics in PEDV-infected pigs, revealing long-term serum antibody persistence. PEDV-specific immunoglobulin (Ig)A and IgG levels were subsequently measured in prepartum serum, oral and rectal swabs, and postpartum colostrum from sows administered with different immunization strategies, including commercial vaccination and feedback. Correlations between the antibody levels in these sample types and colostrum were analyzed in order to facilitate estimation of maternal immunity and prompt adjustment of immunization programs. Results revealed that PEDV-specific IgA and IgG in piglets seroconverted 1 week after infection, peaked at two to 3 weeks, and remained detectable up to 31 weeks. Analysis of 1159 samples collected from sows at various stages across four commercial farms revealed strong correlations between serum and colostrum PEDV IgA and IgG. After the first immunization, the highest correlation coefficients for IgA and IgG were 0.6898 (
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